Evidence map›Paper›PMID 39959331›Full record

ArticleActa clinica Croatica2024

THE IMPACT OF PREOPERATIVE SALIVARY UREA AND SUPEROXIDE DISMUTASE ACTIVITIES ON POSTOPERATIVE PAIN AFTER SURGICAL REMOVAL OF MANDIBULAR THIRD MOLARS.

Nino Grgić, Marko Tarle, Ante Perić, Slavica Potočki, Daria Pašalić, Berislav Perić

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Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nino GrgićDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, University of Zagreb, Dubrava University Hospital, Zagreb, Croatia.
Marko TarleDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, University of Zagreb, Dubrava University Hospital, Zagreb, Croatia.
Ante PerićSchool of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Slavica PotočkiDepartment of Medical Chemistry, Biochemistry and Clinical Chemistry, School of Medicine, University of Zagreb, Zagreb, Croatia.
Daria PašalićDepartment of Medical Chemistry, Biochemistry and Clinical Chemistry, School of Medicine, University of Zagreb, Zagreb, Croatia.
Berislav PerićDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, University of Zagreb, Dubrava University Hospital, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most frequent surgical procedure in oral surgery is extraction of mandibular third molars, which could be associated with postoperative complications such as pain, swelling, and trismus. We aimed to investigate the association of salivary urea and antioxidative enzyme activities with the intensity of postoperative pain after wisdom tooth extraction. This cross-sectional prospective study included 66 subjects (median age 25, range 17-47 years). Salivary urea and superoxide dismutase (SOD) were determined by enzymatic colorimetric tests. The questionnaire for study participants included demographic and history data, as well as data on personal experience of pain in grade 0-10 according to the visual analog scale (VAS). Grading 1-3 was considered as low (VAS-1), 4-6 mild (VAS-2) and 7-10 as severe pain (VAS-3). Moderate positive correlation was recorded between urea concentration and SOD activity in saliva (r=0.46). Moderate negative correlations were found between urea salivary concentration and VAS grading value reported after 12 hours (r=0.51). The concentrations of urea significantly differed among the three VAS categories (p<0.001), whereas salivary SOD activities did not differ among the categories. Preoperative salivary urea concentration and SOD activity might be associated with postsurgical pain after surgical removal of mandibular third molars.

Indexed as

Molar, ThirdPostoperative PainSalivaSuperoxide DismutaseTooth ExtractionUreaAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMandibleMiddle AgedPain MeasurementPreoperative PeriodSuperoxide DismutaseUreaExtraction, toothMolar, thirdPainSuperoxide dismutaseUrea

Identifiers

PMID39959331
PMCPMC11827404

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.