Evidence map›Paper›PMID 39959328›Full record

ArticleActa clinica Croatica2024

EARLY ONSET OF MULTIPLE SCLEROSIS - CLINICAL FEATURES.

Vesna Suknjaja, Lorand Sakalaš, Miroslav Ilin

Abstract read
In one paragraph

Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vesna SuknjajaUniversity Clinical Center of Vojvodina, Department of Neuroinflammation and Demyelinization, Novi Sad, Serbia.
Lorand SakalašUniversity Clinical Center of Vojvodina, Department of Neuroinflammation and Demyelinization, Novi Sad, Serbia.
Miroslav IlinUniversity Clinical Center of Vojvodina, Department of Neuromuscular and Spinal Diseases, Novi Sad, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The onset of multiple sclerosis (MS) in childhood is a diagnostic challenge. The aim of our study was to analyze the parameters of MS with an early onset in relation to the symptoms and course of the disease in adult patients. This study included patients treated with signs and symptoms of initial central nrvous system demyelinating disease, which were divided into a group of 52 patiensts who developed the disease before the age of 18 (children) and another group aged 20-55 years (adults). Children rarely had polysymptomatic onset (p=0.020). The most common initial symptoms in children were optic neuritis (35.3%) and ataxia (35.3%). In the group of adult patients, sensory disturbances (41.6%) were the most common initial symptoms, followed by pyramidal symptoms (37.6%). Monitoring the time of second relapse revealed it to have occurred in 40 (78.4%) pediatric patients and 79 (78.2%) adult patients after a median of 12 months and 9 months, respectively. In conclusion, the initial manifestations of MS in children do not differ much from MS in adults according to the disease characteristics.

Indexed as

Multiple SclerosisAdolescentAdultAge of OnsetChildFemaleHumansMaleMiddle AgedOptic NeuritisYoung AdultClinical presentation of diseaseKey words: Multiple sclerosis, pediatricMultiple sclerosis, adulthood

Identifiers

PMID39959328
PMCPMC11827390

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.