ArticleActa clinica Croatica2024
ELEVATED SERUM C-REACTIVE PROTEIN LEVELS IN COVID-19 PATIENTS WITH SCIATICA: IMPLICATIONS FOR PROGNOSIS AND TREATMENT STRATEGIES.
Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
To the best of our knowledge, no previous study has reported characteristics of C-reactive protein (CRP) levels in COVID-19 patients with comorbidities such as sciatica and lumbar syndrome. The objective of this study was to examine whether CRP levels rose significantly in COVID-19 patients with acute sciatica as compared to COVID-19 patients without it. This prospective study was performed on 147 patients previously diagnosed with COVID-19 infection who were admitted to the COVID hospital. Myalgia (p=0.00008) and lower back pain (p=0.00001) occurred much more frequently in the study group than in the control group. There was a high probability that patients with a previous history of sciatica may experience it again during their stay in COVID-19 hospital and that patients without it would not (p=0.00001). There was a significant correlation between the severity of sciatica and CRP levels (r=0.19, p=0.0174). Our results suggest that serum CRP levels are significantly higher in COVID-19 patients with concomitant sciatica in comparison to patients without sciatic pain, indicating a connection between the increased systemic inflammation in COVID-19 and sciatica. Given that the occurrence of COVID-19 in patients with sciatica is not rare, the knowledge about this matter is of high medical relevance.
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