Evidence map›Paper›PMID 39959263›Full record

ArticleWorld journal of diabetes2025

Clinical significance of Ki-67 in patients with lung adenocarcinoma

Ke Chen, Ge Wang, Jing-Cheng Hu, Ying-Yi Zhou, Hai-Tao Ma

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Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Ke ChenDepartment of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China.
Ge WangDepartment of Endocrine, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China.
Jing-Cheng HuDepartment of Endocrine, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China.
Ying-Yi ZhouDepartment of Endocrine, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China.
Hai-Tao MaDepartment of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China. htma_work@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing number of type 2 diabetes mellitus (T2DM) patients leads to higher rates of morbidity and mortality related to lung cancer.

aimTo investigate the utility of the proliferating cell nuclear antigen Ki-67 in patients with lung adenocarcinoma

methodsOne hundred patients with AIS and T2DM (group A), 100 patients with AIS alone (group B), and 60 patients with benign lung lesions (group C) admitted to the Department of Thoracic Surgery and Endocrinology of the First Affiliated Hospital of Soochow University from November 2021 to December 2022 were enrolled. Ki-67 expression was compared among the groups.

resultsGroup A had significantly higher levels of fasting plasma glucose (FPG), total cholesterol (TC), total triglyceride, low-density lipoprotein cholesterol, glycosylated hemoglobin (HbA1c), and insulin than groups B and C (

conclusionKi-67 expression was higher in patients with AIS complicated by T2DM than in patients with AIS alone. Therefore, detecting the Ki-67 level might assist in the diagnosis of AIS in patients with T2DM.

Indexed as

ImmunohistochemistryKi-67Lung adenocarcinoma in situPrognostic markerType 2 diabetes mellitus

Identifiers

PMID39959263
PMCPMC11718486

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