Evidence map›Paper›PMID 39959162›Full record

ArticleFrontiers in microbiology2025

Preparation and application evaluation of monoclonal antibodies against Monkeypox virus A29 protein.

Ai Xiangjun, Zhang Xinlan, Xu Ye, Tan Chufan, Duan Chen, Liao Nami, Liu Junxi, Qiu Yilan, Hou Defu, Wang Qinglin and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ai Xiangjun *College of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Zhang Xinlan *College of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Xu YeHunan Xuxiang Biotechnology Co., Ltd., Changsha, China.
Tan ChufanCollege of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Duan ChenCollege of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Liao NamiCollege of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Liu JunxiCollege of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Qiu YilanHunan Xuxiang Biotechnology Co., Ltd., Changsha, China.
Hou DefuCollege of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Wang Qinglin *College of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.
Liu Rushi *College of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox virus (MPXV) is a DNA virus belonging to the Orthopoxvirus genus of the Poxviridae family. It causes symptoms similar to Smallpox virus and is a zoonotic virus with widespread prevalence. Antigen detection is a fast and effective detection method. The MPXV A29 protein not only plays an important role in the virus lifecycle but also serves as a promising target for developing specific antibodies, which have significant potential for application in the diagnosis of MPXV. The coding sequences of the MPXV A29 protein, Cowpox virus (CPXV) 163 protein homolog and Vaccinia virus (VACV) A27 protein homolog were chemically synthesized, and all three recombinant proteins were expressed in

Indexed as

antigen detectionchemiluminescence enzyme immunoassaycolloidal gold immunochromatographyMonkeypox virus (MPXV)monoclonal antibodies

Identifiers

PMID39959162
PMCPMC11825512

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.