Evidence map›Paper›PMID 39959090›Full record

ArticleACS omega2025

Potential Antibiotic Resurgence: Consecutive Silver Nanoparticle Applications Gradually Increase Bacterial Susceptibility to Antibiotics.

Maria Maklakova, Luis Jesús Villarreal-Gómez, Ekaterina Nefedova, Nikolay Shkil, Roberto Luna Vázquez-Gómez, Alexey Pestryakov, Nina Bogdanchikova

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Antimicrobial Resistance: How Can We Overcome the Problem?Antibiotics (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria MaklakovaFacultad de Pedagogía e Innovación Educativa, Universidad Autónoma de Baja California, Mexicali, Baja California 21360, Mexico.ORCID https://orcid.org/0000-0002-6438-0052
Luis Jesús Villarreal-GómezFacultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana, Baja California 22260, Mexico.ORCID https://orcid.org/0000-0002-4666-1408
Ekaterina NefedovaSiberian Federal Scientific Centre of Agro-BioTechnologies of the Russian Academy of Sciences, Novosibirsk 630501, Russian Federation.
Nikolay ShkilSiberian Federal Scientific Centre of Agro-BioTechnologies of the Russian Academy of Sciences, Novosibirsk 630501, Russian Federation.
Roberto Luna Vázquez-GómezEscuela de Ciencias de la Salud, Universidad Autónoma de Baja California, Ensenada, Baja California 22890, Mexico.
Alexey PestryakovResearch School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russian Federation.
Nina BogdanchikovaCentro de Nanociencias y Nanotecnología, Universidad Nacional Autónoma de México, Ensenada, Baja California 22800, Mexico.ORCID https://orcid.org/0000-0003-0929-3535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of resistant bacteria has emerged as a critical public health concern due to their ability to resist multiple antibiotics. This study aimed to investigate whether repeated treatments with silver nanoparticles (AgNPs) could gradually decrease bacterial resistance to antibiotics. The methodology involved three consecutive applications of AgNPs on six bacterial strains, followed by assessing their susceptibility to 38 different antibiotics. To our knowledge, the following three phenomena were observed for the first time. (1) During three consecutive AgNP applications, it was revealed that all the studied bacteria gradually became more susceptible to 38 antibiotics; by the end of the treatments, susceptibility had doubled for five bacteria and tripled for

Identifiers

PMID39959090
PMCPMC11822480

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.