Evidence map›Paper›PMID 39959076›Full record

ArticleACS omega2025

Development of a Multienzyme Cascade for Salvianolic Acid A Synthesis from l-Tyrosine.

Mingxi Zhang, Jiayi Zhong, Yuekai Zhang, Weijie Wang, Weirui Zhao, Sheng Hu, Changjiang Lv, Jun Huang, Lehe Mei

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingxi ZhangSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Jiayi ZhongSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Yuekai ZhangSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Weijie WangSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Weirui ZhaoSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.ORCID https://orcid.org/0009-0001-4004-5858
Sheng HuSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Changjiang LvDepartment of Chemical and Biological Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.ORCID https://orcid.org/0000-0003-2294-3520
Jun HuangDepartment of Chemical and Biological Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.ORCID https://orcid.org/0000-0002-1996-4120
Lehe MeiSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salvianolic acid A (SAA) has an important application value for preventing and treating cardiovascular diseases. In this study, we developed a novel multienzyme cascade system for the efficient biosynthesis of SAA, utilizing l-tyrosine (l-Tyr) as a cost-effective and stable starting material. The cascade system incorporated four enzymes: membrane-bound l-amino acid deaminase from

Identifiers

PMID39959076
PMCPMC11822487

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.