ReviewOpen medicine (Warsaw, Poland)2025
Microscopic changes and gross morphology of placenta in women affected by gestational diabetes mellitus in dietary treatment: A systematic review.
Review in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Perioperative blood glucose and energy management in gestational diabetes mellitus: a survey of obstetric staff from selected regions in China.BMC pregnancy and childbirth · 2026Article
- An Update on Umbilical Cord Abnormalities and Associated Thrombosis: A Systematic Review.Clinics and practice · 2026Review
- Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- The Placenta in Gestational Diabetes: An Integrated Review on Metabolic Pathways, Genetic, Epigenetic and Ultrasound Biomarkers for Clinical Perspectives.International journal of molecular sciences · 2026Review
- Diagnostic Utility of Extracellular Levels of Serum Amyloid P and Proteoglycan 4: A Case-Control Study in Gestational Diabetes Mellitus.International journal of general medicine · 2026Article
- Analysis of related factors of spontaneous premature birth in pregnant women with gestational diabetes mellitus and construction of its nomogram risk prediction model.BMC pregnancy and childbirth · 2025Article
- Association between maternal plasma glucose levels during pregnancy and risk of preterm birth: a retrospective study.BMC pregnancy and childbirth · 2025Article
- Falling Third Trimester Insulin Requirements and Adverse Pregnancy Outcomes in Individuals with Pre-Existing Diabetes: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Gene Expression Profile of Placenta and Adipose Tissue in Women with Gestational Diabetes Mellitus.International journal of molecular sciences · 2025Article
- Placental Morphology and Metabolomic Profile in Uncomplicated Metabolically Healthy Obese Pregnancy.Biomedicines · 2025Article
- Evaluation of risk factors for poor wound healing after cesarean delivery in patients with gestational diabetes mellitus: a retrospective study.BMC surgery · 2025Article
- Fetal Pancreatic Circumference as a Predictor of Gestational Diabetes Mellitus During 75 g OGTT.Journal of clinical medicine · 2025Article
- A retrospective analysis of the incidence and risk factors for amniotic fluid embolism in cesarean deliveries.BMC pregnancy and childbirth · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction/objective: Gestational diabetes mellitus (GDM) influences adverse maternal and fetal outcomes. Nutritional therapy and exercise are the first steps to maintain normal glucose levels. During pregnancy, metabolic status influences placental development. Methods: This systematic review focused only on the morphology of the placenta and its microscopic changes in GMD under dietary therapy. A systematic search was performed on the main databases from inception to September 2024 (PROSPERO ID: CRD42024581621). Only original articles on GDM in diet and exercise treatment that reported at least one outcome of interest (microscopic features and macroscopic morphology of the placenta) were included. Results: A total of 716 studies were identified, and nine met the inclusion criteria. The analysis confirmed that despite dietary control, some morphological changes in the placenta, including villus immaturity, chorangiosis, and fibrinoid necrosis, occurred at a different rate. In addition, the included studies reported an increase in placental weight in the diet-controlled GDM group. Conclusion: Therefore, the results of the present qualitative analysis show that pregnant women with diet-controlled GDM, despite adequate glycemic control, abnormal placental development may persist. Our findings remark on the importance of the correct diet-managed GDM pregnancy monitoring due to the placental morphology abnormalities related to GMD.
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