ArticleGland surgery2025
Comparison of endoscopic surgical approaches for total thyroidectomy: a systematic review and Bayesian network meta-analysis.
Article in Gland surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and safety of transoral endoscopic thyroidectomy vestibular approach of papillary thyroid carcinoma: a network meta-analysis.Frontiers in oncology · 2026Pooled it
- Outcomes of transoral endoscopic thyroidectomy vestibular approach versus endoscopic thyroidectomy via areola approach in the treatment of thyroid carcinoma: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Case Report: Diagnosis and treatment strategy for a case of multiple chest wall implantations and neck lymph node metastasis following total areola endoscopic surgery for papillary thyroid carcinoma.Frontiers in oncology · 2026Article
- Case Report: Endoscopic Sistrunk and thyroidectomy via the areola approach in patients with thyroglossal duct cysts and thyroid cancer.Frontiers in oncology · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Different approaches to endoscopic total thyroidectomy are emerging for the treatment of differentiated thyroid cancer, raising clinical concerns about comprehensively evaluating the strengths and weaknesses of these approaches. In this study, we aimed to conduct a network meta-analysis to compare different endoscopic surgical approaches to total thyroidectomy, revealing their respective advantages and limitations. Methods: PubMed, Medline, Cochrane Library, Web of Science, and EMBASE databases were searched from their inception until March 2024. Pairwise meta-analysis and Bayesian network meta-analysis were performed. The surface under the cumulative ranking curve (SUCRA) was used to determine the probability that each surgical approach for the best individual outcome. Results: Twenty-one studies comprising 4,361 patients were included. Based on the SUCRA value, the endoscopic transoral approach (EOA) retrieved the highest number of lymph nodes (LNs) (SUCRA =0.59) among all endoscopic surgical approaches. The minimally invasive video-assisted approach (MIVAA) significantly shortened the operative time (SUCRA =0.77) compared to other endoscopic surgical approaches. MIVAA ranked as the most effective surgical approach for reducing the rate of permanent hypoparathyroidism (SUCRA =0.81) and controlling intraoperative bleeding (SUCRA =0.77). The endoscopic gasless transaxillary approach (EGAA) effectively shortened the hospital stay (SUCRA =0.95) and reduced the rate of transient hypoparathyroidism (SUCRA =0.74). The endoscopic bilateral areola (EBAA) approach ranked as the most effective surgical approach for preventing recurrent laryngeal nerve (RLN) palsy (SUCRA =0.92). Conclusions: The surgical outcomes of endoscopic total thyroidectomy are comparable to those of open thyroidectomy. MIVAA was superior to other endoscopic surgical approaches in terms of operative time, intraoperative bleeding volume, and permanent hypoparathyroidism rate. EOA demonstrated a significant advantage in LNs retrieval. EBAA was superior in protecting the RLN.
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