Evidence map›Paper›PMID 39958847›Full record

ArticleBiomedical optics express2025

Demonstration of femtosecond laser induced refractive index change in silk-fibroin hydrogels.

Quazi Rushnan Islam, Rocio Gutierrez-Contreras, Susana Marcos, Wayne H Knox

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Quazi Rushnan IslamThe Institute of Optics, University of Rochester, Rochester, New York 14627, USA.ORCID https://orcid.org/0009-0005-8783-5725
Rocio Gutierrez-ContrerasInstituto de Optica "Daza de Valdes", Consejo Superior de Investigaciones Cientificas, Madrid, Spain.
Susana MarcosThe Institute of Optics, University of Rochester, Rochester, New York 14627, USA.ORCID https://orcid.org/0000-0001-5511-1697
Wayne H KnoxThe Institute of Optics, University of Rochester, Rochester, New York 14627, USA.

Funding

VISUAL SCIENCE RESEARCH CTR SUPPORTP30EY001319 · NEI · UNIVERSITY OF ROCHESTER · PI Susana Marcos · 1985 to 2026
$17.5M
Interplay between multifocal optics and accommodation: implications for myopia progressionR01EY035009 · NEI · UNIVERSITY OF ROCHESTER · PI Susana Marcos · 2023 to 2026
$2.0M
NEI NIH HHS P30 EY001319NEI NIH HHS R01 EY035009
6 · The paper itself

Abstract

We present induced refractive index changes in biocompatible silk fibroin hydrogels using two different femtosecond laser systems: one using 400 nm at 80 MHz and the other employing 517 nm at 8.3 MHz. Both modalities produced significant index changes, demonstrating the potential to create custom refractive correctors. Additionally, the biocompatibility and environmentally friendly properties of silk-fibroin make it an ideal platform for developing new types of intraocular implants that incorporate tunable refractive corrections.

Identifiers

PMID39958847
PMCPMC11828447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.