ReviewNeurosurgery practice2023
Glymphatics for the Neurosurgeon.
Review in Neurosurgery practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Brain Lymphatic Dysfunction in Subarachnoid Hemorrhage: Pathophysiology and Clinical Implications.Biomolecules · 2026Review
- The Physiology, Pathophysiology, and Clinical Implications of Fluid Resuscitation in Critically Ill Patients.Cureus · 2026Review
- Retrospective Study of Osteopathic Manipulative Treatment on Length of Stay and Opioid Use After Vestibular Schwannoma Resection.Otology & neurotology open · 2025Article
- The basal cisternostomy for management of severe traumatic brain injury: A retrospective study.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- Complexities, Benefits, Risks, and Clinical Implications of Sodium Bicarbonate Administration in Critically Ill Patients: A State-of-the-Art Review.Journal of clinical medicine · 2024Review
- Neurosurgery and the glymphatic system.Acta neurochirurgica · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The glymphatic system is a recently described open vascular system within the brain that allows cerebrospinal fluid to flow into brain parenchyma through perivascular spaces and clears interstitial solutes into the traditional closed vascular system. Although it was initially difficult to study, new evidence suggests that the glymphatic system plays a pivotal role in the pathophysiology of multiple diseases of the central nervous system including traumatic brain injury, hydrocephalus, dementia, and malignancy. In this review, we cover the basics of cerebrospinal fluid dynamics and explore the role of the glymphatic system in traumatic brain injury, post subarachnoid hemorrhage hydrocephalus, normal pressure hydrocephalus, and malignancy. We believe that further understanding of the glymphatic system will lead to new and better therapeutic options for these diseases moving forward.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.