ReviewJournal of multidisciplinary healthcare2025
Glycemic Profile and Clinical Treatment in Patients with Diabetes Mellitus-Tuberculosis: An Update Scoping Review.
Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Article
- Metabolic dysfunction impairs Mycobacterium tuberculosis-specific cytokine and chemokine responses in latent tuberculosis and type 2 diabetes mellitus.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Type 2 diabetes mellitus (T2DM), characterized by chronic hyperglycemia, leads to a decreased immune system and increased susceptibility to infections, such as tuberculosis (TB). However, there are gaps in comprehensive reviews on the relationship between TB and the severity of glycemic control in patients with T2DM, characteristics of glycemic levels, and clinical treatment among patients with DM-TB. Purpose: The primary aim of this study is to explore the association of DM-TB and glycemic control. The secondary aim of this study was to explore the association between DM-TB, successful treatment, and TB severity. Methods: This study used a scoping review following the Arksey and O'Malley framework to provide an overview of glycemic control and clinical treatment of DM-TB. A literature search was performed using three databases, PubMed, Scopus, and Medline, with inclusion criteria for the population of patients with diabetes mellitus and tuberculosis who discuss glycemic control and clinical treatment. Critical appraisal in this study was assessed using the Joanna-Briggs Institute (JBI) critical appraisal tools. Results: We included 16 studies from a total of 741 articles in the initial search. The results of this study showed that patients with DM-TB were more likely to have poor glycemic control than those with diabetes mellitus (DM) without TB. Severe hyperglycemia in patients with DM-TB is associated with an increased risk of TB treatment failure, a long recovery time, and the likelihood of developing multi-drug-resistant tuberculosis (MDR-TB). In addition, patients with DM-TB who did not start TB treatment were more likely to have poorer glycemic control than patients with DM-TB who underwent active TB treatment. Conclusion: Patients with DM-TB, such as MDR-TB, are at a higher risk of poor glycemic control, treatment failure, and clinical severity. Adequate treatment, such as a continuum of glycemic monitoring and early detection and intervention for TB, is needed to improve treatment outcomes.
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