Evidence map›Paper›PMID 39958537›Full record

ArticleWorld journal of gastrointestinal oncology2025

Impact of Linggui Zhugan decoction on microwave ablation outcomes and recurrence in liver cancer.

Rui Huang, Jing Cui

Abstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Rui HuangDepartment of Acupuncture and Moxibustion, Baoji Central Hospital, Baoji 721000, Shaanxi Province, China.
Jing CuiDepartment of Liver Disease, Xi'an Daxing Hospital, Xi'an 710016, Shaanxi Province, China. cuijing20201@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver cancer is one of the most common malignant tumors of the digestive system, and early detection and effective treatment are crucial for improving the prognosis. Microwave ablation (MWA) has shown promising results as a local therapeutic method for liver cancer; however, further improvement of its efficacy remains a key focus of current research.

aimTo evaluate the clinical efficacy of Linggui Zhugan decoction combined with MWA for the treatment of primary liver cancer.

methodsData were collected from 164 patients with primary liver cancer who underwent MWA at our hospital between March 2019 and April 2021. Among them, 79 patients (control group) received routine treatments and 85 patients (research group) received Linggui Zhugan decoction in addition to routine treatment. The clinical efficacy, incidence of adverse reactions, and levels of serum alpha-fetoprotein (AFP), des-γ-carboxy prothrombin (DCP), AFP-L3, total bilirubin (TBil), alanine aminotransferase (ALT), CD4 cell count, CD8 cell count, and CD4/CD8 ratio were compared between the two groups, before and after treatment. The three-year recurrence rates between the two groups were compared, and independent prognostic factors for recurrence were identified.

resultsThe study results revealed that the objective response rate (ORR) in the research group was significantly higher than that in the control group (

conclusionThe combination of Linggui Zhugan decoction with MWA significantly improved the clinical efficacy and long-term prognosis of patients with primary liver cancer.

Indexed as

Clinical efficacyCox regression analysisDisease-free survivalLinggui Zhugan decoctionMicrowave ablationPrimary liver cancer

Identifiers

PMID39958537
PMCPMC11756010

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