Evidence map›Paper›PMID 39958342›Full record

ArticleFrontiers in immunology2025

Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters

Christina Schmidt, Kunjan Harit, Stephan Traidl, Michael Naumann, Thomas Werfel, Lennart M Roesner, Gopala Nishanth, Dirk Schlüter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Proximity labeling of thebioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. T-cell mechanisms in atopic dermatitis.Allergologie select · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christina SchmidtInstitute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Kunjan HaritInstitute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Stephan TraidlDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Michael NaumannInstitute of Experimental Internal Medicine, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Thomas WerfelDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Lennart M RoesnerDepartment of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
Gopala NishanthInstitute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Dirk SchlüterInstitute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In atopic dermatitis (AD), lesional skin is frequently colonized by

Indexed as

Deubiquitinating Enzyme CYLDMacrophagesStaphylococcal InfectionsStaphylococcus aureusSTAT1 Transcription FactorAnimalsFemaleHumansMacrophage ActivationMaleMiceMice, Inbred C57BLMice, KnockoutNF-kappa BSignal TransductionUbiquitinationCYLD protein, humanCYLD protein, mouseDeubiquitinating Enzyme CYLDNF-kappa BSTAT1 protein, humanSTAT1 Transcription Factoratopic dermatitisCYLDmacrophageNF-κBStaphylococcus aureusSTAT1ubiquitin

Identifiers

PMID39958342
PMCPMC11827430

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.