Evidence map›Paper›PMID 39958247›Full record

ArticleJournal of clinical and experimental dentistry2025

Fluoride-Induced Microhardness Changes in Resin-Modified Glass Ionomer Cements: A Comparative Study.

Katherine Susan Rufasto-Goche, E S Cerro-Olivares, N F San Martín-Hilario, Flor M Santander-Rengifo, Alexis G Murillo-Carrasco, María Victoria Lizarbe-Castro

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Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Katherine Susan Rufasto-GocheFaculty of Dentistry, Universidad Nacional Federico Villarreal, Lima, Peru.
E S Cerro-OlivaresFaculty of Dentistry, Universidad Nacional Federico Villarreal, Lima, Peru.
N F San Martín-HilarioFaculty of Dentistry, Universidad Nacional Federico Villarreal, Lima, Peru.
Flor M Santander-RengifoAcademic Program of Dentistry, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Alexis G Murillo-CarrascoImmunology and Cancer Research Group (IMMUCA), Lima, Peru.
María Victoria Lizarbe-CastroPostgraduate School, Universidad Nacional Federico Villarreal, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Resin-modified glass ionomer cement (RM-GIC) is widely used in clinical dental procedures as a restorative material due to its chemical composition. It is known for its strong adhesion to dental structures and its fluoride content. However, fluoride in RM-GIC is insufficient for preventing the formation of carious lesions, making the use of fluoride gel and varnish necessary as preventive strategies. Nevertheless, there may be adverse interactions between RM-GIC and fluoride, which could compromise the properties of these restorative materials. Therefore, it is crucial to understand the physicochemical and biological properties of the products used in dental treatments. This experimental study aimed to evaluate the effect of the following fluorides: 2% neutral sodium fluoride (NaF), 1.23% acidulated phosphate fluoride (APF), and 0.1% fluoride varnish (7700 ppm F) in the mi-cro-hardness of the RM-GIC. Material and Methods: Using GC Fuji II LC-A2, 80 RM-GIC discs measuring 6cm x 4cm were made and immersed in artificial saliva for seven days. Then, the discs were washed, dried, and randomly divided into four groups, and the initial surface microhardness was measured. After that, the discs were immersed in the three fluorides to measure the microhardness for a second time. The average value of the surface microhardness of the RM-GIC in the final phase (exposure to fluorides) of the three experimental study groups is lower than the initial phase (non-exposure to fluorides). Results: There was a significant decrease in the microhardness of the ionomer with the application of the three fluorides ( Conclusions: 2% neutral sodium fluoride, 1.23% acidulated phosphate fluoride, and 0.1% fluoride varnish (7700 ppm F) applied to RM-GIC decreases surface microhardness.

Identifiers

PMID39958247
PMCPMC11829721

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