Evidence map›Paper›PMID 39958139›Full record

ArticleCureus2025

Orbital Myeloid Sarcoma: An Initial Presentation of Acute Myeloid Leukemia With Maturation.

Jordy Batista, Paula L Matías, Virgilio Valerio, Luisa Collado, Félix Contreras Mejuto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jordy BatistaPathology, Laboratorio de Patología Contreras Robledo, Santiago de los Caballeros, DOM.
Paula L MatíasPathology, Laboratorio de Patología Contreras Robledo, Santiago de los Caballeros, DOM.
Virgilio ValerioOphthalmology, Hospital Regional Universitario Jose María Cabral y Báez, Santiago de los Caballeros, DOM.
Luisa ColladoPediatric Oncology, Hospital Infantil Regional Universitario Dr. Arturo Grullón, Santiago de los Caballeros, DOM.
Félix Contreras MejutoPathology, Pontificia Universidad Catolica Madre y Maestra/Clinica Universitaria Union Medica, Santiago de los Caballeros, DOM.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is predominantly an adult disease, with significantly lower incidence in children. Myeloid sarcoma (MS), an extramedullary manifestation of AML, can occur in various tissues, though it is exceptionally rare in the orbit. The variable nature of MS complicates its diagnosis and treatment. In this report, we present the case of an eight-year-old boy who exhibited bilateral proptosis and an orbital mass. Initial investigations revealed thrombocytopenia and leukopenia. Imaging tests confirmed an expansive retroorbital lesion. Immunohistochemistry demonstrated positivity for CD34, CD117, and myeloperoxidase (MPO). The mass was ultimately diagnosed as MS. Subsequent bone marrow analysis confirmed AML. This case highlights that MS, although rare, can serve as an initial presentation of AML in pediatric patients. Epidemiology, diagnosis, treatment, and prognosis for MS were discussed.

Indexed as

acute myeloid leukemia (aml)extra-medullary acute myeloid leukemiamyeloid sarcomaocular chloromaorbital myeloid sarcoma

Identifiers

PMID39958139
PMCPMC11830221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.