Evidence map›Paper›PMID 39958045›Full record

ArticleCureus2025

A Case of Tubulointerstitial Nephritis With Uveitis Diagnosed From Isolated Glucosuria Detected During School Urinary Screening.

Naonori Kumagai, Mami Akamatsu, Yoshiki Kawamura, Haruo Mizuno, Yohei Ikezumi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Naonori KumagaiDepartment of Pediatrics, Fujita Health University School of Medicine, Toyoake, JPN.
Mami AkamatsuDepartment of Pediatrics, Fujita Health University Okazaki Medical Center, Okazaki, JPN.
Yoshiki KawamuraDepartment of Pediatrics, Fujita Health University Okazaki Medical Center, Okazaki, JPN.
Haruo MizunoDepartment of Pediatrics, Fujita Health University School of Medicine, Toyoake, JPN.
Yohei IkezumiDepartment of Pediatrics, Fujita Health University School of Medicine, Toyoake, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of tubulointerstitial nephritis with uveitis (TINU) diagnosed from isolated glucosuria detected during school urinary screening. The patient was a 12-year-old girl in whom glucosuria was detected during school urinary screening using a dipstick; however, urinary protein and occult blood were negative. There were no preceding symptoms of infection or medication. The patient visited the Fujita Health University Okazaki Medical Center two weeks after the school urinary screening for further examination. No edema or skin rash was observed. A urine test showed urinary glucose was positive and urinary β2-microglobulin was high; other values were almost normal. Mild renal dysfunction was observed. There was no hyperglycemia or high HbA1c level; therefore, diabetes mellitus was ruled out. Various autoantibody tests were negative, and the angiotensinogen-converting enzyme level was within the normal range. The patient was clinically diagnosed with idiopathic tubulointerstitial nephritis without a renal biopsy. Renal dysfunction tended to improve gradually after the first visit. Three months after the first visit, conjunctival congestion appeared in the right eye, and the patient was diagnosed with uveitis and eventually with TINU. When performing detailed examinations for urinary glucose, it is necessary to differentiate kidney disease as well as diabetes mellitus. Moreover, it is necessary to recognize that even if the urine dipstick test is negative for protein, it may be positive for low-molecular-weight protein.

Indexed as

dipstickglucosurialow-molecular-weight proteinschool urinary screeningtubulointerstitial nephritis with uveitisβ2-microglobulin

Identifiers

PMID39958045
PMCPMC11828715

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