Evidence map›Paper›PMID 39958030›Full record

ArticleCureus2025

Diffuse Large B-cell Lymphoma Causing Central Airway Obstruction: A Case Report.

Rabi Shrestha, Subekshya Khadka, Hollie Saunders, Scott Helgeson

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rabi ShresthaInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Subekshya KhadkaInternal Medicine, Crestwood Medical Center, Huntsville, USA.
Hollie SaundersPulmonary and Critical Care, Mayo Clinic in Florida, Jacksonville, USA.
Scott HelgesonCritical Care and Pulmonology, Mayo Clinic in Florida, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL) globally, while primary mediastinal B-cell lymphoma (PMBCL) is a rare subtype that may lead to central airway obstruction by compressing or invading the airways. Prompt management of airway obstruction is crucial, as severe cases can be life-threatening if left untreated.  This study reports the case of a 27-year-old man with chronic cough, weight loss, and computed tomography (CT) of the chest revealing a large anterior mediastinal tumor with an extension into the neck and left lung causing airway compression and complete left lung collapse who was found to have PMBCL. The aim of this case report is to show that, in some cases of malignant central airway obstruction, the treatment approach should be based primarily on treating the underlying cause instead of procedural intervention, depending on clinical presentation and history of response to therapy. We highlight the treatment strategy of primary therapy for DLBCL to address central airway obstruction rather than surgical or bronchoscopic intervention.

Indexed as

central airway obstructiondlbcllymphadenopathynhlnon-hodgkin lymphomapmbclprimary diffuse large b-cell lymphomaprimary mediastinal large b-cell lymphoma

Identifiers

PMID39958030
PMCPMC11828711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.