ArticleThe clinical respiratory journal2025
The Linear Association of Chest Radiograph Opacification With Both Respiratory Physiology and Systemic Inflammation in Hospital In-Patients With Covid-19 Infection.
Article in The clinical respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChest radiographs are generally used for diagnostic purposes. They also have potential to quantify disease severity. This analysis tested the hypothesis that there was an association between chest radiograph opacification and measures of respiratory physiological status and systemic inflammation in patients with Covid-19 infection.
methodsData on chest radiograph opacification were compared with concurrent measures of oxygen requirements and saturation and serum C-reactive protein.
resultsData were available from 628 individuals. The median opacification on chest radiographs was 20% (interquartile range 5-45). This was associated both SFR (oxygen saturation/supplementary oxygen) with an r value of -0.38 (95% confidence intervals CI: -0.45 to -31, Pearson's correlation coefficient) and CRP (+0.33; 95% CI: +0.24 to +0.41, Pearson's correlation coefficient).
conclusionChest radiograph opacification scores are associated with both respiratory physiology status and systemic inflammation levels in patients with Covid-19 infection.
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