Evidence map›Paper›PMID 39957281›Full record

ArticleExperimental dermatology2025

Carbon-Based Particles Inhibit Antigen Penetration Into the Skin by Adsorbing the Antigen.

Rin Ichinohe, Ryosuke Segawa, Takahisa Nakajo, Masahiro Hiratsuka, Takeharu Yoshii, Kritin Pirabul, Zhen-Ze Pan, Hirotomo Nishihara, Noriyasu Hirasawa

Abstract read
In one paragraph

Article in Experimental dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rin IchinoheLaboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.
Ryosuke SegawaLaboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.ORCID https://orcid.org/0000-0002-7332-2428
Takahisa NakajoLaboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.
Masahiro HiratsukaLaboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.
Takeharu YoshiiInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi, Japan.ORCID https://orcid.org/0000-0002-1869-6021
Kritin PirabulInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi, Japan.
Zhen-Ze PanAdvanced Institute for Materials Research (WPI-AIMR), Tohoku University, Sendai, Miyagi, Japan.
Hirotomo NishiharaInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi, Japan.
Noriyasu HirasawaLaboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.ORCID https://orcid.org/0000-0002-8062-4838

Funding

Japan Science and Technology AgencyJapan Society for the Promotion of ScienceMinistry of Education, Culture, Sports, Science and Technology
6 · The paper itself

Abstract

In most cases, atopic dermatitis (AD) is induced by allergic inflammation, with antigen penetration into the epithelial tissues of the skin being the first step in AD development. Accordingly, inhibiting the skin penetration of antigens is effective in preventing AD. We evaluated the ability of the following four types of particles to adsorb ovalbumin (OVA): titanium dioxide (TiO

Indexed as

AntigensCarbonDermatitis, AtopicOvalbuminSkinSkin AbsorptionAdsorptionAnimalsFemaleGraphiteHydrogen-Ion ConcentrationImmunoglobulin GInterleukin-4Langerhans CellsMiceMice, Inbred BALB CAntigensCarbonGraphiteImmunoglobulin GInterleukin-4OvalbuminSilicon DioxideTitaniumtitanium dioxideadsorptionatopic dermatitisdendritic cellsimmunoglobulin Einterleukin‐4

Identifiers

PMID39957281
PMCPMC11831095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.