Evidence map›Paper›PMID 39957171›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2025

Study on the diagnostic criteria of syndrome of dampness obstruction in idiopathic membranous nephropathy based on expert consensus.

Wang Dan, Huang Xiaoyan, L I Ping, Hong Xiaofan, Zhang Yumin, Wang Rongrong, Bao Kun, Liang Xing

Abstract readConsensus Statement
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Wang DanNephrology Department, Qianxinan Autonomous Prefecture Hospital of Traditional Chinese Medicine, Xingyi 562400, China.
Huang XiaoyanNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
L I PingNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Hong XiaofanNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Zhang YuminNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Wang RongrongNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Bao KunNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Liang XingNephrology Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.

Funding

Special Funding for Scientific and Technological Research on Traditional Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine: a Multimodular Machine Learning Prediction Model based on Pathological Image-transcriptomics and Traditional Chinese Medicine Syndromes was Used to Investigate the Prognostic Correlation of Long non-coding RNA Molecules in Nephropathy and the Intervention Mechanism of Sanqi Qushi Formula, to Investigate the Pathogenesis and Microbiological Mechanism of Dampness Syndrome of Membranous Nephropathy based on the Microecological Changes of Tongue Coating YN2023MB02Special Funding for Scientific and Technological Research on Traditional Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine: a Multimodular Machine Learning Prediction Model based on Pathological Image-transcriptomics and Traditional Chinese Medicine Syndromes was Used to Investigate the Prognostic Correlation of Long non-coding RNA Molecules in Nephropathy and the Intervention Mechanism of Sanqi Qushi Formula, to Investigate the Pathogenesis and Microbiological Mechanism of Dampness Syndrome of Membranous Nephropathy based on the Microecological Changes of Tongue Coating YN2023MB10the 2020 Guangdong Provincial Science and Technology Innovation Strategy Special Fund: Guangdong-Hong Kong-Macau Joint Lab 2020B1212030006the Guangzhou Science and Technology Plan Project: to Explore the Mechanism of Treating Membranous Nephropathy from the Perspective of Regulating Amino Acid Metabolism Disorder 2023A03J0746the Natural Science Foundation of Guangdong Province: Study on the Mechanism of Sanqi Qushi Prescription Delaying Podocellular Senescence in Membranous Nephropathy based on Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase-Stimulator of Interferon Genes-Nuclear Factor Kappa-B Signaling Pathway 2022A1515011628the Special Project of State Key Laboratory of Dampness Syndrome of Chinese Medicine: Study on Criteria for Diagnosis of Dampness Syndrome of Idiopathic Membranous Nephropathy, Cohort Study on Pathogenesis and Material Basis of Dampness Syndrome of Idiopathic Membranous Nephropathy, Randomized Controlled Clinical Study of Sanqi Qushi Granule in Treatment of Membranous Nephropathy SZ2021ZZ02the Special Project of State Key Laboratory of Dampness Syndrome of Chinese Medicine: Study on Criteria for Diagnosis of Dampness Syndrome of Idiopathic Membranous Nephropathy, Cohort Study on Pathogenesis and Material Basis of Dampness Syndrome of Idiopathic Membranous Nephropathy, Randomized Controlled Clinical Study of Sanqi Qushi Granule in Treatment of Membranous Nephropathy SZ2021ZZ09the Special Project of State Key Laboratory of Dampness Syndrome of Chinese Medicine: Study on Criteria for Diagnosis of Dampness Syndrome of Idiopathic Membranous Nephropathy, Cohort Study on Pathogenesis and Material Basis of Dampness Syndrome of Idiopathic Membranous Nephropathy, Randomized Controlled Clinical Study of Sanqi Qushi Granule in Treatment of Membranous Nephropathy SZ2021ZZ36
6 · The paper itself

Abstract

objectiveTo reach consensus on the diagnostic criteria of syndrome of dampness obstruction in idiopathic membranous nephropathy (IMN) patients by literature research and expert investigation (interviews and a Delphi method).

methodsOur study was consistent with T/CACM 1336-2020. We searched the monographs and references published in the past 40 years (1983-2022), and established the diagnostic criteria pool of water-dampness syndrome and dampness-turbidity syndrome in Traditional Chinese Medicine (TCM) based on literature by using frequency statistics and correlation analysis. Expert investigation (interview method and two rounds of Delphi method) was used to form the diagnostic criteria of water-dampness syndrome and dampness-turbidity syndrome of idiopathic membranous nephropathy. Clinical diagnostic test research was carried out, and compared with "Diagnostic Criteria for dampness syndrome" (T/CACM 1454-2023) to evaluate the authenticity, reliability and clinical application value of the standard.

resultsA total of 122 relevant guides, standards, monographs and documents were included through searching books and Chinese databases. Four experts were interviewed and two rounds of delphi method (75 experts nationwide) were carried out. The experts' opinions are relatively concentrated and the differences are small. Based on the weight of each index, the diagnostic criteria indexes of water-dampness syndrome and dampness-turbidity syndrome were selected. After discussion by the core group members, the diagnostic model of "necessary symptoms and optional symptoms" was established, and the final diagnostic criteria of water-dampness syndrome and dampness-turbidity syndrome were established. One hundred and ninety-one inpatients and outpatients of Guangdong Provincial Hospital of Chinese Medicine from January 2021 to February 2023 were included in Diagnostic test study. There was no statistical difference in gender, age and course of disease (

conclusionsThe consensus-based diagnostic criteria for IMN can be widely incorporated in TCM. A further clinical study will be conducted to analyze the diagnosis value and cut-off score of our IMN criteria.

Indexed as

Glomerulonephritis, MembranousDelphi TechniqueDiagnosis, DifferentialFemaleHumansMaleMedicine, Chinese Traditionalcombination of disease and syndromediagnostic tests, routineglomerulonephritis, membranoussyndrome diagnostic criteriasyndrome of dampness obstruction

Identifiers

PMID39957171
PMCPMC11764929

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