Evidence map›Paper›PMID 39957165›Full record

Trial reportJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2025

Clinical observation of efficacy in adhesive intestinal obstruction with Integrated Chinese (Chaihu Shugan San, ) and Western Medicine: a randomized controlled trial.

Zhang Xin, Cao Jia, Luo Chengping, Fan Yibin, D U Jie

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhang XinGansu University of Chinese Medicine, Lanzhou 730050, China.
Cao JiaDepartment of Traditional Chinese Medicine and Surgery, Nanchong Traditional Chinese Medicine Hospital affiliated to North Sichuan Medical College and Nanchong Hospital of Traditional Chinese Medicine, Nanchong 637000, China.
Luo ChengpingGansu University of Chinese Medicine, Lanzhou 730050, China.
Fan YibinDepartment of Traditional Chinese Medicine and Surgery, Nanchong Traditional Chinese Medicine Hospital affiliated to North Sichuan Medical College and Nanchong Hospital of Traditional Chinese Medicine, Nanchong 637000, China.
D U JieDepartment of Urology and Pelvic Surgery and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.

Funding

Nanchong City Science and Technology Plan Project: the Application of Tongli Shugan Liqi Method in the Treatment of Adhesive Intestinal Obstruction and its Effect on Inflammatory Indicators Interleukin-6, C-reactive protein and Procalcitonin 21YFZJ0108
6 · The paper itself

Abstract

objectiveTo explore the treatment efficacy of integrated Chinese medicine (Chaihu Shugan San, , CSS) and western therapy in the treatment of adhesive intestinal obstruction (AIO), to provide new ideas for the management of the disease.

methodsIn our single-blind randomized controlled study, 120 patients with AIO who were hospitalized in The Affiliated Hospital of China West Normal University Nan Chong Gaoping District People's Hospital from January 2021 to June 2022 and met the inclusion criteria were categorized into the treatment group and the control group. Patients from the control group were administered basic Western Medicine therapy, whereas patients from the treatment group were administered basic Western Medicine therapy plus CSS by gastric tube injection. Subsequently, the time to first anal exhaustion and defecation, time to relief of abdominal distension and pain, days of hospitalization, Traditional Chinese Medicine (TCM) symptom scores, interleukin-6 (IL-6), C-reactive protein (CRP) and procalcitonin (PCT) levels in the 2 groups were recorded and compared.

resultsThe comparison of clinical efficacy of the treatment group were better than the control group. The TCM symptom score was considerably lower in the treatment group; the inflammation indicators CRP, IL-6, and PCT also decreased statistically when comparing the control group. Furthermore, there were significantly reduced in the time to first exhaustion, time to first defecation, time to relief of abdominal pain and distension, and days of hospitalization in the treatment group versus the control group.

conclusionCSS could suppress the inflammatory reaction, reduce days of hospitalization, relieve clinical symptoms in AIO patients with reliable efficacy and high safety and is worthy of clinical application.

Indexed as

Drugs, Chinese HerbalIntestinal ObstructionAdultAgedC-Reactive ProteinFemaleHumansInterleukin-6MaleMedicine, Chinese TraditionalMiddle AgedProcalcitoninTreatment OutcomeYoung AdultC-Reactive ProteinDrugs, Chinese HerbalInterleukin-6ProcalcitoninC-reactive proteininterleukinsintestinal obstructionpost-abdominal surgery

Identifiers

PMID39957165
PMCPMC11764926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.