Evidence map›Paper›PMID 39957017›Full record

ReviewRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

The intriguing perineurial cells - an updated overview of their origin, structure, functions and implication in pathology.

Anne Marie Constantin, Adina Bianca Boşca, Carmen Bianca Crivii, Andreea Crintea, Rada Teodora Sufleţel, Bogdan Cătălin Alexandru, Alina Simona Şovrea

Abstract readReview
In one paragraph

Review in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne Marie ConstantinDiscipline of Histology, Department of Morpho-functional Sciences, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; biancabosca@yahoo.com.
Adina Bianca Boşca
Carmen Bianca Crivii
Andreea Crintea
Rada Teodora Sufleţel
Bogdan Cătălin Alexandru
Alina Simona Şovrea

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paper overviews the uniquely intricate and distinct perineurium that envelops nerve fibers in bundles. It consists of perineurial cells (PCs), connective tissue, and blood vessels. The perineurium creates a microenvironment for efficient signal transmission, protects and maintains neuronal structure and function, and facilitates neuronal repair. PCs are a unique type of myofibroblasts essential for maintaining nerve homeostasis. They act as an effective blood-nerve barrier (BNB), protecting against toxins, infections, and mechanical trauma. Despite their crucial function, the origin, ultrastructure, molecular structure, and functional roles of PCs remain a mystery, making them a fascinating area of study.

Indexed as

Peripheral NervesAnimalsHumansblood-nerve barriermarkersoriginperineurial cellsperineurium ultrastructureperipheral nerves

Identifiers

PMID39957017
PMCPMC11924920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.