Evidence map›Paper›PMID 39956820›Full record

ArticleNature communications2025

TaTCP6 is required for efficient and balanced utilization of nitrate and phosphorus in wheat.

Bin Liu, Weiya Xu, Yanxiao Niu, Qiuyuan Li, Beilu Cao, Jingyi Qi, Yidi Zhao, Yilan Zhou, Long Song, Dongkai Cui and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Transcription Factor TCP9 EnhancesPlants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Bin Liu *Frontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0003-0081-1690
Weiya Xu *Frontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Yanxiao NiuFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Qiuyuan LiFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Beilu CaoFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.ORCID http://orcid.org/0009-0000-7086-1664
Jingyi QiFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Yidi ZhaoFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Yilan ZhouFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Long SongFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0002-5723-302X
Dongkai CuiState Key Laboratory of Crop Stress Biology for Arid Areas, Institute of Future Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Zhenshan LiuState Key Laboratory of Crop Stress Biology for Arid Areas, Institute of Future Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Mingming XinFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0003-4010-4165
Yingyin YaoFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Mingshan YouFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.
Zhongfu NiFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0003-4524-7720
Qixin SunFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0002-3819-6892
Jiewen XingFrontiers Science Center for Molecular Design Breeding (MOE)，Key Laboratory of Crop Heterosis and Utilization (MOE), China Agricultural University, Beijing, China. jiewen.xing@cau.edu.cn.ORCID http://orcid.org/0000-0003-3503-0739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High crop yields require adequate nutrients, particularly nitrate (N) and phosphorus (P). Identifying regulators for efficient N-P utilization is critical in wheat. To explore N-P interactions, we analyze root transcriptomes under varying N-P supplies and identify TaTCP6 as a potential regulator. Nitrate-stimulated TaTCP6 directly triggers the expression of genes related to nitrogen utilization. TaTCP6 competes with TaSPX1/4 for the release of TaPHR2, and also interacts with TaPHR2 to enhance the transactivation capacity of downstream genes. Thus, through the dual roles of TaTCP6, the TCP6-SPX-PHR2 module activates the expression of phosphorus starvation response (PSR) genes. Inhibiting TaTCP6 reduces N and P absorption, negatively impacting yield, while overexpressing TaTCP6 increases grain yield. Notably, overexpression of TaSPX1 suppresses nitrogen utilization genes, especially under low phosphorus conditions. In conclusion, our findings highlight the role of TaTCP6 in coordinating N and P utilization and propose a strategy to reduce fertilizer inputs for sustainable agriculture.

Indexed as

NitratesPhosphorusPlant ProteinsTranscription FactorsTriticumGene Expression Regulation, PlantNitrogenPlant RootsPlants, Genetically ModifiedTranscriptomeNitratesNitrogenPhosphorusPlant ProteinsTranscription Factors

Identifiers

PMID39956820
PMCPMC11830803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.