SynthesisAdvances in nutrition (Bethesda, Md.)2025
Seafood and Neurocognitive Development in Children: A Systematic Review.
Synthesis in Advances in nutrition (Bethesda, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurodevelopmental Outcomes Associated with Early-Life Exposure to Heavy Metals: A Systematic Review.International journal of environmental research and public health · 2025Pooled it
- Brain Foods: A Narrative Review of Food Items and Their Impact on Cognition over the Life Course.Nutrients · 2026Review
- Impact of manganese and metal mixtures in blood, hair, and soil on child adaptive behaviors in Southeast Side Chicago.Environmental research · 2025Article
- Hook, Line, and Thinker: Seafood Nets Benefits for Neurocognitive Development.Advances in nutrition (Bethesda, Md.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seafood is a source of essential nutrients to support neurocognitive development of children and adolescents, but there are concerns about contaminant exposure. Assessing seafood as a food group, rather than a source of nutrients or contaminants, can inform future dietary guidance. This study aimed to update and assess relationships between seafood consumption during childhood and adolescence and neurocognitive development. Three electronic databases were searched until September 2024 to update a previous search from 2000 to 2019. Articles were included if associations were assessed between seafood intake during childhood and adolescence and neurocognitive development outcomes (cognitive development, social-emotional and behavioral development, movement/physical development, language/communication development, depression, anxiety, attention-deficit/hyperactivity disorder, and autism spectrum disorder). All articles were screened at title, abstract, and full-text levels by 2 independent analysts. Data were extracted by 1 analyst, quality checked by a second analyst, and synthesized narratively by 2 analysts independently, considering direction, magnitude, and statistical significance of results for each outcome; discrepancies were resolved via discussion. Risk of bias was assessed using ROBINS-E and ROB 2.0. Certainty of evidence was assessed with Grading of Recommendations Assessment, Development and Evaluation (GRADE). Eighteen articles from 5 short-term (12-16 wk) RCTs conducted in Northern Europe and 9 prospective cohort studies conducted in various countries were included. The evidence suggested a relationship between higher seafood consumption and improved cognitive development outcomes for children and adolescents aged 0-18 y old (GRADE: low). This conclusion was informed by 5 short-term RCTs in which children aged 10 mo to 15 y were provided fatty fish compared with meat, poultry, or fish oil supplements. These RCTs were largely supported by results from 5 longer-term prospective cohort studies. Evidence was inconsistent for social-emotional and behavioral development outcomes and was lacking for other outcomes. Seafood consumption within current recommended intake amounts consumed mainly as fatty fish likely improves cognitive development outcomes in children and adolescents. This review was registered at PROSPERO as CRD42023432844.
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