Evidence map›Paper›PMID 39955732›Full record

ArticleJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2025

History, clinical presentation, therapy, and patient reported outcomes of mucosal lichen planus: a cross-sectional study.

Neda Cramer, Daniel Kromer, Julia M Bootsveld, Sabine Sennhenn-Kirchner, Sascha Gerdes, Wiebke Sondermann, Katharina Assaf, Matthias Goebeler, Dagmar Wilsmann-Theis, Claudia Günther and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. History, clinical presentation, therapy, and patient reported outcomes of mucosal lichen planus: a cross-sectional study.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Neda CramerDepartment of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0009-0007-9130-1288
Daniel KromerCytel Inc., Berlin, Germany.
Julia M BootsveldDepartment of Dermatology, Technische Universität Dresden, University Hospital, Dresden, Germany.
Sabine Sennhenn-KirchnerDepartment of Oral and Maxillofacial Surgery, University Medical Centre Göttingen, Göttingen, Germany.
Sascha GerdesDepartment of Dermatology, University Hospital Schleswig-Holstein, Kiel, Germany.
Wiebke SondermannDepartment of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany.
Katharina AssafDepartment of Dermatology and Allergology, University Hospital Bonn, Bonn, Germany.ORCID 0009-0001-5802-4908
Matthias GoebelerDepartment of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.ORCID 0000-0001-7095-9848
Dagmar Wilsmann-TheisDepartment of Dermatology and Allergology, University Hospital Bonn, Bonn, Germany.ORCID 0000-0002-5594-7192
Claudia GüntherDepartment of Dermatology, Technische Universität Dresden, University Hospital, Dresden, Germany.ORCID 0000-0002-4330-1861
Christian KromerDepartment of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0003-2197-4907
Rotraut MössnerDepartment of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0003-2476-7647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesMucosal lichen planus (LP) is a chronic inflammatory disease. The patient's journey can be arduous as diagnosis and therapy are challenging. PATIENTS AND

methodsIn this cross-sectional study, a wide range of characteristics of the patient's journey were assessed and evaluated from a total of 72 patients with mucosal LP who were treated in the dermatology departments of six German university medical centers between 02/2022 and 07/2023.

resultsOn average, 18.1 months elapsed between the onset of symptoms and diagnosis. Until the correct diagnosis was made, an average of 3.1 different physicians of the same or different specialties were consulted. 28.1% of patients also had cutaneous involvement. Therapeutically, 68% of patients received at least one systemic drug. Both topical (90%, 65/72) and systemic (oral, 50% of patients, 36/72; intravenous, 33%, 24/72) glucocorticoids were most frequently used. Systemic agents were most often discontinued due to ineffectiveness (46%, 50/110). Satisfaction with treatment was highest for intravenous and topical glucocorticoids (moderate to high satisfaction: 59% and 36%, respectively), and lowest for retinoids with 8%.

conclusionsThis study indicates that there might be a lack of diagnostic awareness among physicians and the unmet need for effective systemic treatment options.

Indexed as

GlucocorticoidsLichen PlanusLichen Planus, OralAgedCross-Sectional StudiesFemaleGermanyHumansMaleMiddle AgedPatient Reported Outcome MeasuresPatient SatisfactionGlucocorticoidscross‐sectional studymucosal lichen planusoral lichen planuspatient's journeytherapytreatment satisfaction

Identifiers

PMID39955732
PMCPMC11979553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.