Evidence map›Paper›PMID 39955501›Full record

ArticleBMC urology2025

Flexible ureteroscopy combined with potassium sodium hydrogen citrate(PSHC) intervention improves the stone-free rate(SFR) for 20-30 mm uric acid renal stones.

Ru Huang, Min-Jun Jiang, Jian-Chun Chen, Zhi-Jun Cao, Zhen-Fan Wang, Zheng Ma, Guo-Bing Lin, Chen Xu

Abstract read
In one paragraph

Article in BMC urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ru Huang *Department of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China.
Min-Jun Jiang *Department of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China.
Jian-Chun Chen *Department of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China.
Zhi-Jun CaoDepartment of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China.
Zhen-Fan WangDepartment of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China.
Zheng MaDepartment of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China.
Guo-Bing LinDepartment of Urology, The First Affiliated Hospital of Zhejiang Chinese Medicine University, Hangzhou, 310053, China. lguob9835@126.com.
Chen XuDepartment of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, 215200, China. chenadoc@126.com.

Funding

the Priority Disease of Suzhou LCZX202231the Youth Pproject of "Gusu healthy" GSWS2022110
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of combining flexible ureteroscopy (FURS) with potassium sodium hydrogen citrate(PSHC) for the treatment of 20-30 mm uric acid renal stones.

methodsA retrospective analysis of outcomes of patients with 20-30 mm uric acid renal stones who were treated with FURS and holmium lithotripsy was conducted between July 2021 and May 2024. Of them, 60 patients accepted FURS combined potassium sodium hydrogen citrate(PSHC) therapy while 70 patients underwent the FURS procedure alone. The demographic data, stone characteristics, surgical details, and perioperative outcomes of the patients were assessed retrospectively. Stone-free status was defined as the complete absence of stones on computed tomography.

resultsTotally 130 patients were enrolled and analyzed in this study. No significant differences were found between the two groups in terms of gender, age, body mass index, comorbidities, stone burden, stone density, number of stones, or laterality. The mean operation time, American Society of Anesthesiologists (ASA) score, postoperative stay, and complication rate were also similar between the groups. The combined group incurred higher costs (p < 0.01),but it achieved significantly higher stone-free rate and Wisconsin Stone Quality of Life Questionnaire score at 4 weeks post-operatively (96.7% vs. 85.7%,p = 0.029;124.63 vs. 114.44,p < 0.01). Additionally, the combined group had a significantly higher urine pH at 4 weeks postoperatively compared to the non-combined group (6.63 vs. 5.50, p < 0.01).

conclusionCompared to a single procedure, FURS combined with PSHC therapy is an effective and safe treatment for 20-30 mm uric acid renal stones.

Indexed as

CitratesKidney CalculiUreteroscopyUric AcidAdultAgedCombined Modality TherapyFemaleHumansMaleMiddle AgedPotassium CitrateRetrospective StudiesTreatment OutcomeUreteroscopesCitratesPotassium CitrateUric AcidFURSOral therapyPSHCUric acid stones

Identifiers

PMID39955501
PMCPMC11829543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.