Evidence map›Paper›PMID 39955463›Full record

ArticleNPJ digital medicine2025

Smartphone administered pulsed radio frequency energy therapy for expedited cutaneous wound healing.

Mengxia Yu, Hongjia Yang, Haoteng Ye, Shuhuang Lin, Yujie Lu, Haoqiang Deng, Lulu Xu, Yongxin Guo, John S Ho, Terry Tao Ye

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mengxia YuDepartment of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0002-0973-7952
Hongjia YangDepartment of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China.
Haoteng YeDepartment of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China.ORCID http://orcid.org/0009-0002-2961-9627
Shuhuang LinSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Yujie LuDepartment of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China.
Haoqiang DengDepartment of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China.
Lulu XuThe Wolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough, UK.
Yongxin GuoDepartment of Electrical Engineering, City University of Hong Kong, Hong Kong, China. yongxin.guo@nus.edu.sg.
John S HoDepartment of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore. johnho@nus.edu.sg.ORCID http://orcid.org/0000-0002-9458-9033
Terry Tao YeDepartment of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China. yet@sustech.edu.cn.ORCID http://orcid.org/0000-0002-4359-3550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulsed radio frequency energy (PRFE) therapy is a non-invasive, electromagnetic field-based treatment modality successfully used in clinical applications. However, conventional PRFE devices are often bulky, expensive, and require extended treatment durations, limiting patient adherence and efficacy. Here, we present a lightweight, cost-effective wearable PRFE system consisting of a flexible electronic bandage and a smartphone. The bandage, mainly composed of an NFC Frequency Doubler (NFD) and a Radiofrequency Energy Radiator (RER), is powered and administered by the smartphone to generate 27.12 MHz radio wave pulses, for simplified, smartphone-enabled PRFE therapy. Its ultra-flexible, battery-free design supports personalized wound care at a low-cost (<US$1). Both electromagnetic field simulation and measurement demonstrated that the proposed PRFE bandage achieves the field strength of clinical-grade PRFE equipment. In rat full-thickness wound models, PRFE therapy improved wound closure rates by ~20%, with enhanced re-epithelialization and angiogenesis compared to controls.

Identifiers

PMID39955463
PMCPMC11830092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.