Evidence map›Paper›PMID 39955450›Full record

ArticleAnnals of surgical oncology2025

Safety of Non-robotic Transoral Surgeries for Pharyngolaryngeal Cancer: A Risk Factor Analysis of Complications Using Nationwide Claims Data.

Yoshiki Watanabe, Kayoko Mizuno, Yo Kishimoto, Koji Kawakami, Koichi Omori

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Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yoshiki WatanabeDepartment of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kayoko MizunoDepartment of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yo KishimotoDepartment of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Koji KawakamiDepartment of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Koichi OmoriDepartment of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. omori@ent.kuhp.kyoto-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-robotic transoral surgery (NRTOS) is the mainstream approach for pharyngolaryngeal cancer resection in Japan, whereas the da Vinci surgical system is not widely used. NRTOS employs reusable instruments, resulting in significantly lower costs than those of transoral robotic surgery (TORS). Given the comparable oncological outcomes, this study aimed to investigate the risk factors for complications and mortality following NRTOS as an alternative to TORS. PATIENTS AND

methodsThis retrospective cohort study utilized Japanese claims data from diagnosis procedure combination and receipt databases. Data from patients who underwent NRTOS between April 2020 and December 2022 were collected. The primary outcomes were postoperative bleeding, dysphagia, and laryngopharyngeal edema.

resultsAmong the 336 included patients, 88.7% were male, with a median age of 72 years. The incidence rates of bleeding, dysphagia, and laryngopharyngeal edema after NRTOS were 3.3%, 4.2%, and 8.0%, respectively. Univariate logistic regression analysis revealed that history of hypertension [odds ratio (OR): 9.82, 95% confidence interval (CI): 1.24-77.50] was a possible risk factor for postoperative bleeding, while a disease stage ≥ T2 (OR: 5.37, 95% CI: 1.52-19.00), a body mass index < 18.5 kg/m

conclusionsNRTOS demonstrated relatively low complication and mortality rates, establishing it as a safe technique for pharyngolaryngeal cancer resection.

Indexed as

Laryngeal NeoplasmsNatural Orifice Endoscopic SurgeryPharyngeal NeoplasmsPostoperative ComplicationsAgedAged, 80 and overDeglutition DisordersFemaleFollow-Up StudiesHumansJapanMaleMiddle AgedPostoperative HemorrhagePrognosisRetrospective StudiesComplicationLaryngeal cancerPharyngeal cancerRisk factorTransoral robotic surgeryTransoral surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.