Evidence map›Paper›PMID 39955409›Full record

ArticleScientific reports2025

Performance of the Nottingham hip fracture score (NHFS) as a predictor of 30-day mortality after proximal femur fracture in an older people Brazilian cohort.

Flávio Cruz Ferro, Marcos Adriano Garcia Campos, Thais Caroline Silva Picolli, Vania de Sá Mayoral, Victoria Moralez Soares, Jessica Caroline Ferreira, Lucas Dias Borges Peres, Theodor Terra Mayer Tibeau, Victor El Chihimi Bernardi, David Nascimento Pereira and 13 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Flávio Cruz FerroInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Marcos Adriano Garcia CamposGlobal Emergency Medicine Innovation and Implementation Research Center, Department of Emergency Medicine, Duke University School of Medicine, Durham, NC, USA.
Thais Caroline Silva PicolliInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Vania de Sá MayoralInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Victoria Moralez SoaresInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Jessica Caroline FerreiraInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Lucas Dias Borges PeresInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Theodor Terra Mayer TibeauInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Victor El Chihimi BernardiInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
David Nascimento PereiraInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
David Nicoletti GumieiroHospital das Clínicas da Faculdade de Medicina de Botucatu, Secretaria de Saúde do Estado de São Paulo, São Paulo, Brazil.
Emilio Carlos CurcelliHospital das Clínicas da Faculdade de Medicina de Botucatu, Secretaria de Saúde do Estado de São Paulo, São Paulo, Brazil.
Lais Helena Navarro E LimaDepartment of Anaesthesiology, Perioperative, and Pain Medicine, University of Manitoba, Winnipeg, MB, Canada.
Paulo do Nascimento JuniorDepartment of Surgical Specialties and Anaesthesiology, Medical School, São Paulo State University (UNESP), Botucatu, Brazil.
Taline LazzarinInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Raquel Simões BallarinInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Marina Politi OkoshiInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Marcos Ferreira MinicucciInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Sergio Alberto Rupp de PaivaInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Adam Lee GordonWolfson Institute of Population Health, Queen Mary University of London, London, UK.
Opinder SahotaNottingham University Hospitals NHS Trust, Nottingham, UK.
Filipe Welson Leal PereiraInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil.
Paula Schmidt AzevedoInternal Medicine Department, Medical School, São Paulo State University (UNESP), Prof. Mário Rubens Guimarães Montenegro Avenue, Botucatu, SP, 18618-970, Brazil. schmidt.azevedo@unesp.br.ORCID 0000-0002-5843-6232

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico PIBICConselho Nacional de Desenvolvimento Científico e Tecnológico PQ 311383/2021-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/15147-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/00225-4
6 · The paper itself

Abstract

Perioperative risk assessment helps inform clinical practice for older people with hip fractures. This is a cohort study, where perioperative risk screening, including NHFS, was performed at admission, followed by an evaluation of 30-day outcomes. 503 patients were included, 73% female, 79.4 ± 9.3 years old; 58% presented extracapsular and 42% intracapsular fractures, with a 30-day mortality of 9%. The NHFS was higher in the patients who died at 5.6 ± 1.1 compared to survivals at 4.3 ± 1.5 (p-value < 0.001). NHFS > 4 was associated with 30-day mortality observed by Cox regression adjusted by fracture type: HR 4.55 (95% CI 2.10-9.82) (p-value < 0.001) and Kaplan-Meyer Curve (HR 3.94; 95% CI 2.19-7.07; p-value < 0.001). ROC curve showed the accuracy of NHFS in explaining 30-day mortality (AUC 0.74; 95% CI 0.67-0.81). Complications were higher among patients with NHFS > 4. The performance of NHFS was better than the traditional perioperative risk ASA score. Therefore, NHFS can be implemented in real-world clinical practice to estimate the 30-day mortality risk for hip fracture in older patients in Brazil. NHFS > 4 is critical for 30-day mortality and complications; this cutoff helps inform clinical practice. The present study might motivate other centers to consider NHFS in their perioperative risk assessment routine.

Indexed as

Hip FracturesAgedAged, 80 and overBrazilCohort StudiesFemaleHumansMaleProximal Femoral FracturesRisk AssessmentRisk FactorsROC CurveFemur fractureHip fractureMortalityOlder peopleRiskSurgery

Identifiers

PMID39955409
PMCPMC11830071

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.