Evidence map›Paper›PMID 39955387›Full record

ArticleScientific reports2025

Impact of the right ventricular mechanical pattern assessed by three-dimensional echocardiography on adverse outcomes following cardiac surgery.

Marius Keller, Alexandra Fábián, Andrea Bandini, Ádám Szijártó, Zoltán Tősér, Béla Merkely, Tim Heller, Marcia-Marleen Dürr, Peter Rosenberger, Attila Kovács and 1 more

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marius Keller *Department of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076, Tuebingen, Germany. marius.keller@med.uni-tuebingen.de.
Alexandra Fábián *Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, 1122, Hungary.
Andrea BandiniDepartment of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076, Tuebingen, Germany.
Ádám SzijártóHeart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, 1122, Hungary.
Zoltán TősérArgus Cognitive, Inc, 35 South Main Street, Hanover, NH, 03755, USA.
Béla MerkelyHeart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, 1122, Hungary.
Tim HellerDepartment of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076, Tuebingen, Germany.
Marcia-Marleen DürrDepartment of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076, Tuebingen, Germany.
Peter RosenbergerDepartment of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076, Tuebingen, Germany.
Attila Kovács *Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, 1122, Hungary.
Harry Magunia *Department of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Risk stratification for cardiac surgery is a cornerstone of perioperative management. While the prognostic impact of severe right ventricular (RV) dysfunction is well understood, the added value of the RV mechanical pattern regarding risk prediction remains unknown. We sought to prospectively validate the predictive value of 3D RV mechanics for adverse perioperative outcomes. The clinical and echocardiographic parameters of 439 retrospectively selected patients who underwent various types of cardiac surgery and 3D transesophageal echocardiography were investigated to determine their associations with a composite endpoint of an unfavorable postoperative outcome. Tricuspid regurgitation, 2D RV strains, and 3D measures of left ventricular (LV) and RV function were associated with the composite endpoint. Multivariable logistic regression models revealed that only tricuspid regurgitation, LV ejection fraction and 3D RV global longitudinal strain (GLS) were independently associated with the endpoint. By applying the model to the data of 128 prospectively enrolled patients, only 3D RV GLS remained an independent predictor. A RV GLS cutoff of -17.4% was found to be associated with a 3-fold increased risk for adverse outcomes. This led us to conclude that RV longitudinal deformation derived from 3D echocardiography is predictive of adverse outcomes and should be incorporated in perioperative risk stratification.

Indexed as

Cardiac Surgical ProceduresEchocardiography, Three-DimensionalHeart VentriclesPostoperative ComplicationsVentricular Dysfunction, RightVentricular Function, RightAgedFemaleHumansMaleMiddle AgedRetrospective StudiesCardiac surgeryRightventricular functionRisk predictionThree-dimensional echocardiographyTransesophageal echocardiography

Identifiers

PMID39955387
PMCPMC11830065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.