ArticleThe Journal of rheumatology2025
Association Between Depressive Symptoms and Self-Reported Physical Activity in Persons With Knee Osteoarthritis.
Article in The Journal of rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Self-reported sedentary time and its influencing factors among patients with knee osteoarthritis: a cross-sectional survey.Scientific reports · 2025Article
- Quality and reliability of osteoarthritis-related health information on short video platforms: a cross-sectional comparative study of TikTok and Bilibili.Frontiers in digital health · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveDepressive symptoms are common in patients with knee osteoarthritis (KOA) and reduce energy, motivation, and movement; thus, declines in physical activity (PA) could worsen as clinical disease progresses. The objective was to evaluate the longitudinal relationship between depressive symptoms and self-reported PA over time among persons with KOA.
methodsThe sample included Osteoarthritis Initiative participants (N = 2602) with radiographic disease (Kellgren-Lawrence grade ≥ 2). Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale (CES-D; score ≥ 16) at baseline and first 3 follow-up visits. Self-reported PA was assessed with the Physical Activity Scale for the Elderly (PASE) at the first 4 follow-up visits. Marginal structural models controlling for time-invariant and time-varying confounders evaluated the longitudinal relationship between depressive symptoms and PASE
resultsDepressive symptoms were associated with lower PA (β -0.09; 95% CI -0.20 to 0.01) over time, but the relationship was not statistically significant. When including depressive symptoms-by-time interactions, the relationship was nonlinear from the first to fourth follow-up visit: visit 1 = -0.18 (95% CI -0.33 to -0.02), visit 2 = -0.05 (95% CI -0.22 to 0.11), visit 3 = -0.01 (95% CI -0.19 to 0.16), and visit 4 = -0.11 (95% CI -0.29 to 0.08). However, the interaction terms were not statistically significant.
conclusionDepressive symptoms may contribute to worse self-reported PA levels in persons with KOA. Future research should determine whether lower physical function is a further sequela of decreased PA related to depressive symptoms.
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