ArticleMarine biotechnology (New York, N.Y.)2025
Lipid- and Multivariate-Based Analyses to Determine Cell Response to pH Variations and Buffer Composition.
Article in Marine biotechnology (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Study on Early Pregnancy Diagnosis of Sows Based on Body Fluid Metabolite Detection Combined with Machine Learning Models.Veterinary sciences · 2026Article
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Authors and funding
2 authors.
Funding
Abstract
During marine bioprocess development, pH control is of paramount importance. In shake flasks, aerobic fermentations usually have no pH control except from the buffering effect provided by buffers in the medium. However, the use of traditional buffers, such as phosphate buffer, can lead to the precipitation of medium components. Good's buffers may be a sound alternative. Using Serratia rubidaea cells and their production of prodigiosin as model system, several Good's buffers were tested and compared to phosphate buffer. Lipidomics analysis in conjugation with statistical multivariate analysis was performed to determine the cellular response to pH variations and buffer composition. Biomass productivity was similar when using the different buffers, but prodigiosin production was highly influenced and was highest with MES buffer at pH 5.5, reaching 249.8 mg/L, which corresponds to 43.7 mg/g
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