Evidence map›Paper›PMID 39954106›Full record

ArticleMikrochimica acta2025

A synchronous fluorescence biosensor mediated by hydrogen-bonding interaction for highly selective detection of dopamine.

Lingling Li, Xinru Zhang, Xianglei Chang, Xianhua Meng, Weifeng Wang, Ying Zhang, Aimei Yang, Junli Yang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lingling LiSchool of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, P. R. China.
Xinru ZhangSchool of Pharmacy, Lanzhou University, Lanzhou, 730000, P. R. China.
Xianglei ChangCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China.
Xianhua MengCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China.
Weifeng WangCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China.
Ying ZhangCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China. zhangying@licp.cas.cn.
Aimei YangSchool of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, P. R. China. aimeiyang@163.com.
Junli YangCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China. yangjl@licp.cas.cn.

Funding

Major Program of the Lanzhou Institute of Chemical Physics, CAS ZYFZFX-6The Key Research and Development Project of Gansu Province 20YF3FA023the National Natural Science Foundation of China 32270419
6 · The paper itself

Abstract

A highly selective and sensitive silicon nanoparticles (Si NPs) biosensor was developed for dopamine (DA) detection utilizing synchronous fluorescence spectroscopy (SFS). Si NPs were synthesized via a one-step hydrothermal method, utilizing 3-aminopropyltriethoxysilane (APTES) as the silane precursor and polyethyleneimine (PEI) as the reducing agent. The Si NPs exhibited a spherical morphology, with an average diameter of 3.7 nm. Additionally, the Si NPs demonstrated remarkable fluorescent properties. When integrated into the DA detection process utilizing SFS, the synchronous fluorescence spectrum of the DA system exclusively exhibits a peak at 530 nm, whereas systems involving epinephrine and norepinephrine both display peaks at 484 nm and 530 nm. Consequently, this detection system exhibits a high capacity for effectively differentiating between DA and other catecholamines (epinephrine and norepinephrine), ensuring a high degree of specificity in the detection process. Additionally, this combined approach also presents a strong linear relationship between the enhancement of synchronous fluorescence intensity (F

Indexed as

Biosensing TechniquesDopamineFluorescent DyesHumansHydrogen BondingLimit of DetectionNanoparticlesPolyethyleneiminePropylaminesSilanesSiliconSpectrometry, Fluorescenceamino-propyl-triethoxysilaneDopamineFluorescent DyesPolyethyleneiminePropylaminesSilanesSiliconDopamineSilicon nanoparticlesSynchronous fluorescence

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.