Evidence map›Paper›PMID 39954055›Full record

SynthesisInternational journal of legal medicine2025

Global lens of Willems' method for dental age estimation: where we are and where we are going - umbrella review.

Daniela da Costa Nóbrega Brasil, Débora Duarte Moreira, Bianca Marques Santiago, Walbert de Andrade Vieira, Oksana Avdeenko, Luiz Renato Paranhos, Ademir Franco

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of legal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniela da Costa Nóbrega BrasilDivision of Forensic Dentistry, Faculdade São Leopoldo Mandic, Rua José Rocha Junqueira 13, Office 03, Block E, Swift Postal code: 13.045-755, Campinas, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0007-9502-998X
Débora Duarte MoreiraDivision of Oral Radiology, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-2024-9976
Bianca Marques SantiagoDepartment of Clinical and Social Dentistry, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.ORCID http://orcid.org/0000-0001-9559-913X
Walbert de Andrade VieiraDepartment of Dentistry, Centro Universitário das Faculdades Associadas de Ensino (UNIFAE), São João da Boa Vista, SP, Brazil.ORCID http://orcid.org/0000-0001-8872-2865
Oksana AvdeenkoDepartment of Therapeutic Stomatology, Sechenov University, Moscow, Russian Federation.ORCID http://orcid.org/0000-0002-9806-6213
Luiz Renato ParanhosDepartment of Community and Social Dentistry, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.ORCID http://orcid.org/0000-0002-7599-0120
Ademir FrancoDivision of Forensic Dentistry, Faculdade São Leopoldo Mandic, Rua José Rocha Junqueira 13, Office 03, Block E, Swift Postal code: 13.045-755, Campinas, São Paulo, SP, Brazil. ademir.junior@slmandic.edu.br.ORCID http://orcid.org/0000-0002-1417-2781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This umbrella review aimed to evaluate the evidence behind the Willems method for dental age estimation and detect methodological limitations in the existing systematic reviews. The study followed the Preferred Reporting Items for Overviews of Reviews (PRIOR), with the protocol registered in PROSPERO (CRD42023487745). Seven databases, including grey literature sources, were searched (Medline/PubMed, Scopus, LILACS, SciELO, Web of Science, Open Grey and Open Access Theses and Dissertations). Systematic reviews of cross-sectional studies on the Willems method were included. Two calibrated reviewers independently conducted study selection, data extraction, quality assessment (AMSTAR-2) and risk of bias (ROBIS). Five systematic reviews published between 2017 and 2022 were included. Combined sample sizes ranged from 9347 to 17,741 individuals aged 2.2 to 18 years. Meta-analyses reported minor overestimations in dental age, with differences varying by sex and ethnicity. However, significant methodological shortcomings were identified, such as lack of protocol registration, limited search strategies, and inadequate assessment of the risk of bias. All systematic reviews were rated as critically low quality and with a high risk of bias. The Willems method was deemed appropriate for dental age estimation by most studies, but methodological limitations of existing systematic reviews underscore the need for more rigorous research and improved standards.

Indexed as

Age Determination by TeethAdolescentChildCross-Sectional StudiesHumansAgeChildrenForensic dentistryRadiographTooth

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.