Evidence map›Paper›PMID 39953968›Full record

ArticleACS chemical biology2025

Visualizing Intracellular Localization of Natural-Product-Based Chemical Probes Using Click-Correlative Light and Electron Microscopy.

Eva Schaller, Julian Hofmann, Pamela Maher, Christian Stigloher, Michael Decker

Abstract read
In one paragraph

Article in ACS chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eva SchallerPharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg, Am Hubland, Würzburg D-97074, Deutschland.
Julian HofmannPharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg, Am Hubland, Würzburg D-97074, Deutschland.
Pamela MaherThe Salk Institute for Biological Studies, 10010 N Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0003-0694-0610
Christian StigloherZentrale Abteilung für Mikroskopie/Imaging Core Facility, Biozentrum/Theodor-Boveri-Institut, Julius-Maximilians-Universität Würzburg, Am Hubland, Würzburg D-97074, Germany.
Michael DeckerPharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg, Am Hubland, Würzburg D-97074, Deutschland.ORCID 0000-0002-6773-6245

Funding

Using geroscience to understand and treat Alzheimer's diseaseR01AG069206 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MAHER, PAMELA ANNE · 2020 to 2024
$4.0M
The Contribution of Kidney Disease to Age-Associated Cognitive DeclineRF1AG061296 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MAHER, PAMELA ANNE · 2019 to 2019
$3.2M
NIA NIH HHS R01 AG069206NIA NIH HHS RF1 AG061296
6 · The paper itself

Abstract

Flavonoids such as sterubin and fisetin─and derivatives thereof─show strong neuroprotective effects

Indexed as

Click ChemistryFlavonoidsFlavonolsAnimalsBiological ProductsCell LineEndoplasmic ReticulumHippocampusMiceMicroscopy, ElectronMicroscopy, FluorescenceMolecular ProbesBiological ProductsfisetinFlavonoidsFlavonolsMolecular Probes

Identifiers

PMID39953968
PMCPMC13670529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.