Evidence map›Paper›PMID 39953666›Full record

SynthesisClinical and translational science2025

Risk of major adverse cardiovascular events in CYP2C19 LoF genotype guided clopidogrel against alternative antiplatelets for CAD patients undergoing PCI: Meta-analysis.

Mohitosh Biswas, Murshadul Alam Murad, Maliheh Ershadian, Most Sumaiya Khatun Kali, Chonlaphat Sukasem

Abstract readMeta-Analysis
In one paragraph

Synthesis in Clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohitosh BiswasDepartment of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh.ORCID 0000-0003-1432-7701
Murshadul Alam MuradDepartment of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh.ORCID 0009-0006-6113-0687
Maliheh ErshadianDivision of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Most Sumaiya Khatun KaliDepartment of Pharmacy, Daffodil International University, Dhaka, Bangladesh.ORCID 0000-0002-3363-0303
Chonlaphat SukasemDivision of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID 0000-0003-0033-5321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selection of rational antagonists of P2Y

Indexed as

ClopidogrelCoronary Artery DiseaseCytochrome P-450 CYP2C19Percutaneous Coronary InterventionPlatelet Aggregation InhibitorsAllelesGenotypeHumansPrasugrel HydrochloridePurinergic P2Y Receptor AntagonistsRisk FactorsTicagrelorTreatment OutcomeClopidogrelCYP2C19 protein, humanCytochrome P-450 CYP2C19Platelet Aggregation InhibitorsPrasugrel HydrochloridePurinergic P2Y Receptor AntagonistsTicagrelor

Identifiers

PMID39953666
PMCPMC11828747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.