ArticleJournal of orthopaedic surgery and research2025
Relationship between muscle size and density and proximal femoral bone mineral density in elderly men with hip fractures across different age groups.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Sarcopenia index is a superior prognostic marker to creatinine-cystatin C ratio in older adults with hip fracture.Journal of orthopaedic surgery and research · 2025Article
- The influence of different genders on the relationship between the size and density of paravertebral muscles and subcutaneous adipose tissue and the proximal femoral bone in elderly people with hip fractures.BMC musculoskeletal disorders · 2025Article
- Bone mineral content determined by energy X-ray absorptiometry correlates with handgrip strength in Latin American divers.Frontiers in public health · 2025Article
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2 authors.
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Abstract
aimsTo investigate the relationship between muscle size and density and bone mineral density (BMD) of the proximal femur in elderly men with hip fractures (HF) across different age groups.
methodsQuantitative computed tomography (QCT) was conducted on the hip joints of 300 male patients with low-energy acute HF to measure areal BMD (aBMD). Concurrently, the cross-sectional area and density of the gluteal and thigh muscles surrounding the hip were assessed. Multivariable linear regression models were utilized to evaluate the associations between muscle characteristics and BMD across various age groups and fracture types.
resultsAfter adjusting for BMI covariates, all measures of aBMD in the femoral neck fracture (FNF) group were significantly positively correlated with mid-thigh muscle (MM) area in patients aged 75 years and older (P < 0.05). In contrast, thigh muscle density did not show a significant correlation. In patients younger than 75 years, there was a positive correlation between MM density and total hip (TH) aBMD in the FNF group (B, 9.077; 95% CI, 1.577-16.577; P = 0.018). In the ITF group, no muscle parameters were found to be associated with aBMD.
conclusionsOur study demonstrated that in the FNF group aged 75 and older, thigh muscle size, but not density, was positively correlated with the BMD parameters of the proximal femur. Therefore, thigh muscle size may serve as a more clinically significant target for preventing FNF in older men.
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