Evidence map›Paper›PMID 39953570›Full record

ArticleBMC chemistry2025

Simultaneous determination of five nitroimidazole antimicrobials in pharmaceuticals using HPLC-ESM and QAMS methods.

Baoxia Fang, Dan Jiang, Sicen Wang, Fuchao Chen

Abstract read
In one paragraph

Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Baoxia Fang *Sinopharm Dongfeng General Hospital, School of Pharmaceutical Sciences, Hubei University of Medicine, 16# Daling Road, Shiyan, Hubei, 442008, PR China.
Dan Jiang *Sinopharm Dongfeng General Hospital, School of Pharmaceutical Sciences, Hubei University of Medicine, 16# Daling Road, Shiyan, Hubei, 442008, PR China.
Sicen WangSinopharm Dongfeng General Hospital, School of Pharmaceutical Sciences, Hubei University of Medicine, 16# Daling Road, Shiyan, Hubei, 442008, PR China. wangsc@mail.xjtu.edu.cn.
Fuchao ChenSinopharm Dongfeng General Hospital, School of Pharmaceutical Sciences, Hubei University of Medicine, 16# Daling Road, Shiyan, Hubei, 442008, PR China. dfyycfc@163.com.

Funding

Hubei Provincial Natural Science Foundation of China 2024AFD097the Technology Key Program of Shiyan, China 21Y75
6 · The paper itself

Abstract

A green, rapid, and simple HPLC-External standard method (ESM) and a quantitative analysis of multi- components with a single-marker (QAMS) method were established for the simultaneous determination of five nitroimidazole antimicrobials (Metronidazole sodium chloride injection, Tinidazole injection, Ornidazole sodium chloride injection, Morinidazole sodium chloride injection, Secnidazole tablets) in pharmaceutical preparations. The five specified drugs were chromatographed via HPLC on a ZORBAX SB-C

Indexed as

External standard methodHPLCNitroimidazole antimicrobialsQuantitative analysis of multi-components with a single-markerSimultaneous determination

Identifiers

PMID39953570
PMCPMC11829564

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.