Evidence map›Paper›PMID 39953536›Full record

SynthesisSystematic reviews2025

Attention-deficit/hyperactivity disorder and post-traumatic stress disorder adult comorbidity: a systematic review.

Hussein M Magdi, Ali D Abousoliman, Ateya Megahed Lbrahim, Mohamed Gamal Elsehrawy, Heba Emad El-Gazar, Mohamed Ali Zoromba

Abstract readSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hussein M MagdiNorth London NHS Foundation Trust, London, United Kingdom.ORCID 0000-0001-9983-5195
Ali D AbousolimanCollege of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Ateya Megahed LbrahimCollege of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Mohamed Gamal ElsehrawyCollege of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Heba Emad El-GazarNursing Administration Department, Faculty of Nursing, Port Said University, Port Said, Egypt.
Mohamed Ali ZorombaCollege of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia. zromba2010@mans.edu.eg.ORCID 0000-0002-4298-1121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth attention-deficit hyperactivity disorder (ADHD) and post-traumatic stress disorder (PTSD) are complicated illnesses that sometimes co-occur in children and adults with significant negative influence on a person's life and general well-being.

aimThis study aims to conduct a systematic review that investigates the comorbidity of PTSD and ADHD in the adult population.

methodsA comprehensive search was conducted across five electronic databases (PsycNET, Cochrane, PubMed, Google Scholar, and ClinicalTrials.gov) between October 5 and 20, 2023, using predefined keywords including "ADHD," "PTSD," and "comorbidity." Studies were included if they involved adult participants (≥ 18 years) with both ADHD and PTSD diagnoses. Two independent reviewers conducted screening and data extraction. No meta-analysis was performed due to heterogeneity in study designs. The results were synthesized qualitatively.

resultsOut of 818 identified studies, 21 met the inclusion criteria. Studies reported an increased risk of developing PTSD in individuals with ADHD, with the prevalence of comorbidity ranging between 28 and 36%. ADHD in PTSD patients was associated with greater psychosocial impairment, more severe PTSD symptoms, and functional difficulties. Treatment approaches, including pharmacotherapy (atomoxetine, Vyvanse) and mindfulness training, showed potential benefits for managing comorbid symptoms.

conclusionsADHD and PTSD commonly co-occur in adults, leading to more severe clinical outcomes. Early diagnosis and effective treatment of ADHD may reduce the risk of developing PTSD. Further research is needed to explore the underlying mechanisms and optimal treatment strategies for individuals with ADHD/PTSD comorbidity. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42023479631.

Indexed as

Attention Deficit Disorder with HyperactivityStress Disorders, Post-TraumaticAdultComorbidityHumansADHDAdultsComorbidityPTSDSystematic reviewTreatment

Identifiers

PMID39953536
PMCPMC11829347

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.