Evidence map›Paper›PMID 39953516›Full record

ArticleBMC public health2025

The relationship between gender identity and depressive symptoms in adolescents: a moderated mediation model of self-efficacy and family functioning.

Chenyu Hou, Hanchun Yan, Zhibiao Xiang, Chenyang Leng, Haojuan Tao, Zhening Liu, Hui Lei

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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenyu Hou *Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, 410011, China.
Hanchun Yan *Xiangya School of Medicine, Central South University, Changsha, Hunan, 410013, China.
Zhibiao XiangDepartment of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, 410011, China.
Chenyang LengXiangya School of Medicine, Central South University, Changsha, Hunan, 410013, China.
Haojuan TaoDepartment of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, 410011, China. taohaojuan@csu.edu.cn.
Zhening LiuDepartment of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, 410011, China.
Hui LeiDepartment of Applied Psychology, College of Education, Hunan Agricultural University, Changsha, 410128, China.

Funding

Central South University Student Innovation Training Project XCX2021068
6 · The paper itself

Abstract

backgroundGender identity is associated with adolescent depression, but the relationship remains unclear. To further clarify the relationship between gender identity and mental health, this study targets adolescents with significant fluctuations in gender identity, constructs a moderated mediation effect model, examines the relationship between gender identity and depression, and explores the mediating role of self-efficacy and the moderating role of family functioning, to provide scientific references for proposing effective psychological interventions for different gender identity groups.

methodsUsing whole group convenience sampling method, 2341 students from a school in Changsha, Hunan Province, were selected for the survey, and the Patient Health Questionnaire-9 items, the Family Care Index Scale, the General Self-Efficacy Scale-Schwarzer, and gender identity-related questions were used for the assessment of mental health.

resultsThe prevalence of depression was 40.5% among transgender adolescents, which was significantly higher than that of cisgender adolescents (15.6%). At the same time, gender identity, self-efficacy, family functioning, and depression constituted a moderated mediation model, with family functioning moderating the posterior path of this mediation process. Specifically, self-efficacy was progressively less predictive of depression as family functioning increased.

conclusionTransgender adolescents showed significantly poorer mental health than cisgender adolescents. There was a partial mediating effect of self-efficacy between gender identity and adolescent depression, with family functioning moderating the latter half of this mediation effect. This study advances our understanding of the relationship between depression and self-efficacy or family functioning in adolescents of different gender identities.

Indexed as

DepressionFamily RelationsGender IdentitySelf EfficacyAdolescentChinaFemaleHumansMaleSurveys and QuestionnairesDepressionFamily functioningGender identitySelf-efficacy

Identifiers

PMID39953516
PMCPMC11827441

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.