Evidence map›Paper›PMID 39953450›Full record

ArticleBMC nephrology2025

Membranoproliferative glomerulonephritis with syphilis involvement and possible Hepatitis B virus contribution: a case report.

Yan Pan, Jiqiang Zhang, Lei Liu, Ruiping Zhao, Tiekun Li, Weidong Chen

Abstract readCase Reports
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan PanNephrology Department, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233000, China.
Jiqiang ZhangNephrology Department, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233000, China.
Lei LiuNephrology Department, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233000, China.
Ruiping ZhaoNephrology Department, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233000, China.
Tiekun LiNanjing Kingmed Center for Clinical Laboratory CO, Ltd., Nanjing, China.
Weidong ChenNephrology Department, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233000, China. cwd2012@163.com.

Funding

Anhui provincial Key Research and Development Project 202004j07020011Key Project of Natural Science Foundation of Bengbu Medical College No. 2022byzd041
6 · The paper itself

Abstract

backgroundSyphilis, a sexually transmitted disease, presents with a wide range of clinical manifestations. As the global rate of syphilis infection continues to rise, so does the incidence of syphilis-associated nephritis. Characterized by diverse clinical and pathological features, the disease shows a good response to penicillin treatment. This article presents the case of a 46-year-old Chinese male patient exhibiting edema, hematuria, proteinuria, and a tendency towards rapidly progressive glomerulonephritis (RPGN). The patient was diagnosed with membranoproliferative glomerulonephritis (MPGN), with syphilis being a likely etiology and co-infection with Hepatitis B virus (HBV). He was treated with benzathine penicillin for three weeks, followed by low-dose glucocorticoids and mycophenolate mofetil (MMF) for subsequent treatment, leading to a significant improvement in his condition.

conclusionHighlighting the significance of syphilis as a cause of nephritis and emphasizing the importance of timely diagnosis and treatment can greatly alleviate the patient's condition. Additionally, the role of Hepatitis B virus as a contributing factor in the development of nephritis should not be overlooked. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Glomerulonephritis, MembranoproliferativeHepatitis BSyphilisCoinfectionGlucocorticoidsHepatitis B virusHumansMaleMiddle AgedMycophenolic AcidGlucocorticoidsMycophenolic AcidHepatitis B virusMembranoproliferative glomerulonephritisPenicillinRapidly progressive glomerulonephritisSyphilis

Identifiers

PMID39953450
PMCPMC11829439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.