Evidence map›Paper›PMID 39953424›Full record

ArticleBMC pregnancy and childbirth2025

Determinants of new-onset postpartum preeclampsia among mothers who delivered in hospitals in the South Gondar Zone, Northwest Ethiopia: a multicenter case-control study.

Dagne Addisu, Yekaba Mitiku, Wassie Yazie Ferede, Begizew Yimenu Mekuriaw, Besfat Berihun Erega, Lakachew Yismaw Bazezew, Tegegne Wale Belachew, Selamawit Girma Tadesse, Yitayal Ayalew Goshu, Belaynew Alemye Mengistie and 3 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Dagne AddisuDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia. addisudagne7@gmail.com.
Yekaba MitikuDepartment of Midwifery, Debre Tabor Comprehensive Specialized Hospital, Debre Tabor, Ethiopia.
Wassie Yazie FeredeDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Begizew Yimenu MekuriawDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Besfat Berihun EregaDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Lakachew Yismaw BazezewDepartment of Pediatrics and Neonatal Nursing, Debre Tabor University, Debre Tabor, Ethiopia.
Tegegne Wale BelachewDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Selamawit Girma TadesseDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Yitayal Ayalew GoshuDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Belaynew Alemye MengistieDepartment of Midwifery, Debre Tabor Comprehensive Specialized Hospital, Debre Tabor, Ethiopia.
Maru MekieDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Agernesh Dereje MiskerDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.
Gedefaye Nibret MihretieDepartment of Midwifery, Debre Tabor University, Debre Tabor, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew-onset postpartum preeclampsia has emerging as a significant public health concern in Ethiopia, with a notable increase in incidence in the study area. While substantial research exists on antepartum preeclampsia, data on the determinants of new-onset postpartum preeclampsia are limited. Therefore, this study aimed to investigate determinants of new-onset postpartum preeclampsia among mothers who gave birth at hospitals in the South Gondar Zone, Northwest Ethiopia.

methodsAn unmatched case-control study was conducted with 355 postpartum mothers (89 cases and 266 controls). A multistage sampling method was used to select the study participants. Data were collected using structured questionnaires and medical chart reviews, and analyzed using SPSS Version 27. Binary logistic regression (bivariable and multivariable analysis) was used to identify factors associated with new-onset postpartum preeclampsia. Statistical significance was set at p < 0.05, and strength of associations were measured using adjusted odds ratios (AOR) with 95% confidence intervals (CIs).

resultNew-onset postpartum preeclampsia was significantly associated with several factors, including advanced maternal age, fewer antenatal care (ANC) visits, contraceptive use, physical inactivity, a history of multiple gestations, and gestational diabetes mellitus. Specifically, maternal age ≥ 40 years (AOR = 11.63, 95% CI: 4.24-31.86), fewer than four ANC visits (AOR = 8.45, 95% CI: 3.96-18.05), contraceptive use (AOR = 4.04, 95% CI: 1.26-13.37), irregular physical activity (AOR = 4.05, 95% CI: 1.32-12.44), physical inactivity (AOR = 8.25, 95% CI: 4.62-19.29), a history of multiple gestations (AOR = 2.66, 95% CI: 1.26-5.60), and gestational diabetes mellitus (AOR = 17.79, 95% CI: 7.72-40.95) were identified as key determinants.

conclusionsAdvanced maternal age, fewer ANC visits, contraceptive use, physical inactivity, multiple gestations, and gestational diabetes were strongly associated with new-onset postpartum preeclampsia. Increased ANC visits and postpartum monitoring are essential for early detection and management of postpartum preeclampsia. Additionally, promoting physical activity should be incorporated into maternal health strategies to reduce the incidence of new onset postpartum preeclampsia.

Indexed as

Postpartum PeriodPre-EclampsiaAdultCase-Control StudiesDiabetes, GestationalEthiopiaFemaleHumansMaternal AgePregnancyPregnancy, MultiplePrenatal CareRisk FactorsYoung AdultDeterminants of new onset postpartum preeclampsiaEthiopiaMulticenter case–control studyNew-Onset postpartum preeclampsiaRisk factors for postpartum preeclampsiaSouth Gondar Zone

Identifiers

PMID39953424
PMCPMC11829449

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.