Evidence map›Paper›PMID 39953344›Full record

Trial reportLasers in medical science2025

Evaluating the effectiveness and safety of pulsed dye laser alone, the combination of pulsed dye laser and botulinum toxin type A, and the combination of pulsed dye laser and triamcinolone injection in the treatment of hypertrophic and keloid scars: a three-arm randomized controlled clinical trial.

Najmolsadat Atefi, Mohammad Amin Jafari, Masoumeh Roohaninasab, Abbas Dehghani, Alireza Jafarzadeh, Seyed Babak Peighambari, Arash Peighambari, Azadeh Goodarzi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Najmolsadat Atefi *Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID http://orcid.org/0000-0003-1053-2441
Mohammad Amin Jafari *Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID http://orcid.org/0000-0003-0617-2412
Masoumeh RoohaninasabDepartment of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID https://orcid.org/0000-0002-2862-6422
Abbas DehghaniDepartment of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID https://orcid.org/0000-0001-9277-3606
Alireza JafarzadehDepartment of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID http://orcid.org/0000-0001-5878-9778
Seyed Babak PeighambariDepartment of Biomedical Engineering, Texas A & M University, Texas, USA.ORCID https://orcid.org/0009-0001-1398-0111
Arash PeighambariDepartment of Computer Science, California State University San Marcos, California, USA.ORCID https://orcid.org/0009-0000-6231-4652
Azadeh GoodarziDepartment of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran. azadeh_goodarzi1984@yahoo.com.ORCID http://orcid.org/0000-0002-1249-4429

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the efficacy and safety of pulsed dye laser (PDL) alone, the combination of PDL and botulinum toxin type A (BTA) injection, and the combination of PDL and triamcinolone injection in the treatment of hypertrophic scars and keloids. In this three-arm, single-blind randomized controlled clinical trial, 10 patients over 18 years old with hypertrophic scars or keloids were enrolled. Each patient had at least 3 lesions, each measuring at least 10 × 10 square centimeters or 10 centimeters long. In the first treatment session, each of the 3 lesions was randomly assigned to one of three interventions: PDL (control), PDL with BTA injection (at a concentration of 2 units/cm

Indexed as

Botulinum Toxins, Type ACicatrix, HypertrophicKeloidLasers, DyeLow-Level Light TherapyTriamcinoloneAdultCombined Modality TherapyFemaleHumansMaleMiddle AgedSingle-Blind MethodTreatment OutcomeYoung AdultBotulinum Toxins, Type ATriamcinoloneBotulinum toxinClinical trialEfficacyHypertrophic scarKeloidPulsed dye laserSafetyTriamcinolone

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.