ArticleArchives of virology2025
Molecular evidence for goose astrovirus 2 and goose astrovirus 3 coinfection in goslings with gout.
Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Gosling gout is usually considered to be caused by goose astrovirus 2 (GoAstV-2); however, goose astrovirus 3 (GoAstV-3) has also been shown to play a pathogenic role in this disease. Here, we developed new assays for specific detection of goose astroviruses, including GoAstV-2- and GoAstV-3-specific reverse transcription (RT)-PCR and real-time fluorescence quantitative PCR (RT-qPCR) assays. These assays revealed coinfection with GoAstV-2 and GoAstV-3 in 19 (57.6%) out of 33 cases examined, with GoAstV-2 producing 1,000- to 100,000-fold higher viral loads than GoAstV-3. These findings will stimulate further studies on the roles of GoAstV-2 and GoAstV-3 in the occurrence of gosling gout.
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