Evidence map›Paper›PMID 39953205›Full record

ArticleScientific reports2025

Chlorogenic acid inhibits Pseudomonas toxin pyocyanin and activates mitochondrial UPR to protect host against pathogen infection.

Yi Xiao, Linlu Li, Chao Han, Tingyun Huang, Shuangjie Ren, Xiaoqin Wang, Qianlu Xing, Fang Liu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Chelerythrine enhances anti-fungi immunity inFrontiers in immunology · 2026
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi Xiao *Institute of Life Sciences, Zunyi Medical University, Zunyi, 563000, Guizhou, China. xiaoyizmu@126.com.
Linlu Li *Institute of Life Sciences, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Chao Han *Institute of Life Sciences, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Tingyun HuangDepartment of Pediatric, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Shuangjie RenInstitute of Life Sciences, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Xiaoqin WangDepartment of Pediatric, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Qianlu XingDepartment of Pediatric, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China. 729333665@qq.com.
Fang LiuInstitute of Life Sciences, Zunyi Medical University, Zunyi, 563000, Guizhou, China. liufangzmu@126.com.

Funding

National Natural Science Foundation of China 32060033National Natural Science Foundation of China 32160037
6 · The paper itself

Abstract

Mitochondria are required for protecting host against pathogenic bacteria by activating mitochondrial unfolded protein response (UPR

Indexed as

Chlorogenic AcidMitochondriaPseudomonas aeruginosaPseudomonas InfectionsPyocyanineUnfolded Protein ResponseAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsImmunity, InnateMiceCaenorhabditis elegans ProteinsChlorogenic AcidPyocyanineCaenorhabditis elegansChlorogenic acidInnate immunityMiceMitochondrial unfolded protein response (UPRmt)

Identifiers

PMID39953205
PMCPMC11829045

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.