Evidence map›Paper›PMID 39953192›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Posterior fossa astroblastoma: a case report of an extremely rare tumor with challenging diagnosis in a child and a review of literature.

Ehab Shabo, Saida Zoubaa, Gerrit H Gielen, Ralf Clauberg, Christian Wispel, Torsten Pietsch, Hartmut Vatter, Sevgi Sarikaya-Seiwert

Abstract readCase ReportsReview
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ehab ShaboDepartment of Neurosurgery, Friedrich-Wilhelms-University, University Hospital Bonn, Venusberg-Campus 1, Bonn, 53127, Germany. Ehab.Shabo@ukbonn.de.ORCID 0000-0003-2269-5707
Saida ZoubaaDepartment of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn, Bonn, 53127, Germany.
Gerrit H GielenDepartment of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn, Bonn, 53127, Germany.
Ralf ClaubergDepartment of Neuroradiology, University Hospital Bonn, Bonn, 53127, Germany.
Christian WispelSection of Pediatric Neurosurgery, Department of Neurosurgery, Rheinische, Friedrich-Wilhelms-University, University Hospital Bonn, Bonn, 53127, Germany.
Torsten PietschDepartment of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn, Bonn, 53127, Germany.
Hartmut VatterDepartment of Neurosurgery, Friedrich-Wilhelms-University, University Hospital Bonn, Venusberg-Campus 1, Bonn, 53127, Germany.
Sevgi Sarikaya-SeiwertSection of Pediatric Neurosurgery, Department of Neurosurgery, Rheinische, Friedrich-Wilhelms-University, University Hospital Bonn, Bonn, 53127, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 7-year-old boy presented to the hospital with recurrent nausea and vomiting over 2 weeks. A cranial MRI revealed a large heterogeneous lesion in the posterior fossa extending from the fourth ventricle to the foramen magnum with contact to the brainstem. The lesion showed moderate diffusion restriction and multiple small cystic components. The child underwent gross total resection. The primary histological findings suggested proliferative active tumor without further definition. The extended histological examination 3 weeks later confirmed the diagnosis of astroblastoma. Due to complete resection and full recovery of the patient, watchful waiting with radiological follow-up was recommended. Astroblastoma is an extremely rare tumor especially in the posterior fossa. However, it should be considered as a differential diagnosis in every tumor presenting the discussed radiological and histological features, especially in young aged patients.

Indexed as

Cranial Fossa, PosteriorInfratentorial NeoplasmsNeoplasms, NeuroepithelialChildHumansMagnetic Resonance ImagingMaleAstroblastomaDiagnosisPosterior fossa

Identifiers

PMID39953192
PMCPMC11828785

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.