Evidence map›Paper›PMID 39953149›Full record

ArticleEuropean radiology2025

Comparison of magnetocardiography and coronary computed tomographic angiography for detection of coronary artery stenosis and the influence of calcium.

Tingting Wu, Xin Zhao, Lanxin Feng, Shuwen Yang, Haoran Xing, Zhao Ma, Xueyao Yang, Min Zhang, Ming Ding, Yi He and 3 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Magnetocardiography in diagnosis of MINOCA: a case series.Frontiers in cardiovascular medicine · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tingting Wu *Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xin Zhao *Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Lanxin FengDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Shuwen YangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Haoran XingDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhao MaDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xueyao YangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Min ZhangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Ming DingSchool of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Yi HeDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Chenchen TuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. tcc2033@163.com.
Xiantao SongDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. song0929@mail.ccmu.edu.cn.ORCID http://orcid.org/0000-0002-0294-879X
Hongjia ZhangDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Funding

Beijing Hospitals Authority 'sailing' Program YGLX202323Beijing Nova Program 20220484222Capital's Funds for Health Improvement and Research 2024-2-2066'Deng Feng' Training Program DFL20220603Project of the Beijing Lab for Cardiovascular Precision Medicine PXM2018_014226_000013
6 · The paper itself

Abstract

objectivesThis study aimed to compare the diagnostic performance of magnetocardiography (MCG) and coronary computed tomography angiography (CCTA) in detecting coronary artery stenosis in relation to coronary calcification.

methodsA total of 587 patients who underwent invasive coronary angiography (ICA) with both CCTA and MCG between September 1, 2022, and August 31, 2023, were included. The patients were divided into three subgroups based on their coronary artery calcium score (CACS), namely less than 100, 100-400, and 400 and above, as determined by the Agatston score. The diagnostic sensitivity, specificity, accuracy, and the area under the receiver operating characteristic curve (ROC) of MCG, CCTA, and the combined diagnostic model (CCTA + MCG) were compared across all CACS subgroups.

resultsAccording to ICA, 481 out of 587 patients (81.94%) had ischemia. The area under the ROC curve (AUC) of MCG for detecting ischemia was 0.80, with a sensitivity of 74.64% and specificity of 84.91% for all patients. In the different CACS subgroups, the diagnostic specificity of CCTA notably decreased (78.57% vs 24.13% vs 17.46%), while that of MCG remained stable (92.86% vs 86.21% vs 82.54%). The diagnostic accuracy of MCG and the combined diagnostic model was better than that of CCTA when CACS was ≥ 400 (77.22% vs 67.22% vs 58.89%). The AUC values of MCG, CCTA, and the combined model in the CACS ≥ 400 subgroups were 0.78, 0.49, and 0.71, respectively.

conclusionsThe diagnostic performance of MCG is less affected by CACS than that of CCTA. MCG and the combined model demonstrate better performance than CCTA alone in detecting coronary artery stenosis, particularly in cases with CACS ≥ 400. KEY POINTS: Question How does the diagnostic performance of MCG compare with coronary computed tomographic angiography (CCTA) at different levels of calcification scores (CACS)? Findings MCG demonstrated better performance than CCTA in detecting coronary artery stenosis, particularly in patients with high CACS. Clinical relevance MCG or the MCG and CCTA combined model can be used to improve the noninvasive imaging diagnostic performance for detecting coronary artery stenosis and reduce unnecessary ICA, especially for patients with high calcification scores.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary StenosisMagnetocardiographyVascular CalcificationAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityCoronary artery calcium scoreCoronary artery diseaseCoronary computed tomography angiographyMagnetocardiography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.