Evidence map›Paper›PMID 39953053›Full record

ArticleScientific reports2025

Ontology-guided machine learning outperforms zero-shot foundation models for cardiac ultrasound text reports.

Suganya Subramaniam, Sara Rizvi, Ramya Ramesh, Vibhor Sehgal, Brinda Gurusamy, Hikmatullah Arif, Jeffrey Tran, Ritu Thamman, Emeka C Anyanwu, Ronald Mastouri and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Suganya SubramaniamUniversity of California, San Francisco, 521 Parnassus Avenue Rm 6222, San Francisco, CA, 94143, USA.
Sara RizviUniversity of California, San Francisco, 521 Parnassus Avenue Rm 6222, San Francisco, CA, 94143, USA.
Ramya RameshUniversity of California, Berkeley, Berkeley, CA, USA.
Vibhor SehgalUniversity of California, Berkeley, Berkeley, CA, USA.
Brinda GurusamyUniversity of California, Berkeley, Berkeley, CA, USA.
Hikmatullah ArifUniversity of Washington, Seattle, WA, USA.
Jeffrey TranUniversity of Arizona, Tucson, AZ, USA.
Ritu ThammanUniversity of Pittsburgh, Pittsburgh, PA, USA.
Emeka C AnyanwuUniversity of Pennsylvania, Philadelphia, PA, USA.
Ronald MastouriIndiana University, Indianapolis, IN, USA.
G Burkhard MackensenUniversity of Washington, Seattle, WA, USA.
Rima ArnaoutUniversity of California, San Francisco, 521 Parnassus Avenue Rm 6222, San Francisco, CA, 94143, USA. rima.arnaout@ucsf.edu.

Funding

Toward efficient performance for deep learning on medical imagingR01HL150394 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Rima Arnaout · 2020 to 2026
$6.2M
NHLBI NIH HHS R01 HL150394
6 · The paper itself

Abstract

Big data can revolutionize research and quality improvement for cardiac ultrasound. Text reports are a critical part of such analyses. Cardiac ultrasound reports include structured and free text and vary across institutions, hampering attempts to mine text for useful insights. Natural language processing (NLP) can help and includes both statistical- and large language model based techniques. We tested whether we could use NLP to map cardiac ultrasound text to a three-level hierarchical ontology. We used statistical machine learning (EchoMap) and zero-shot inference using GPT. We tested eight datasets from 24 different institutions and compared both methods against clinician-scored ground truth. Despite all adhering to clinical guidelines, institutions differed in their structured reporting. EchoMap performed best with validation accuracy of 98% for the first ontology level, 93% for first and second levels, and 79% for all three. EchoMap retained performance across external test datasets and could extrapolate to examples not included in training. EchoMap's accuracy was comparable to zero-shot GPT at the first level of the ontology and outperformed GPT at second and third levels. We show that statistical machine learning can map text to structured ontology and may be especially useful for small, specialized text datasets.

Indexed as

EchocardiographyMachine LearningNatural Language ProcessingData MiningHumansEchocardiography reportLarge language modelsMachine learningNatural language processingOntology

Identifiers

PMID39953053
PMCPMC11828978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.