Evidence map›Paper›PMID 39952996›Full record

ArticleScientific reports2025

RENEB interlaboratory comparison for biological dosimetry based on dicentric chromosome analysis and cobalt-60 exposures higher than 2.5 Gy.

Martin Bucher, David Endesfelder, Stefan Pojtinger, Ans Baeyens, Joan-Francesc Barquinero, Christina Beinke, Laure Bobyk, Eric Gregoire, Rositsa Hristova, Juan S Martinez and 16 more

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Martin BucherDepartment of Effects and Risks of Lonising and Non-Ionising Radiation, Federal Office for Radiation Protection (BfS), Oberschleissheim, Germany. mbucher@bfs.de.ORCID 0000-0002-7643-0192
David EndesfelderDepartment of Effects and Risks of Lonising and Non-Ionising Radiation, Federal Office for Radiation Protection (BfS), Oberschleissheim, Germany.ORCID 0000-0002-1859-3727
Stefan PojtingerDepartment for Dosimetry for Radiation Therapy and Diagnostic Radiology, Physikalisch- Technische Bundesanstalt (PTB), Braunschweig, Germany.ORCID 0000-0001-6397-4572
Ans BaeyensRadiobiology Lab, Department of Human Structure and Repair, Ghent University, Gent, Belgium.ORCID 0000-0002-2578-7917
Joan-Francesc BarquineroUnitat d'Antropologia Biològica, Departament de Biologia Animal, Biologia Vegetal i Ecologia, Universitat Autònoma de Barcelona, Bellaterra, E-08193, Catalonia, Spain.ORCID 0000-0003-0084-5268
Christina BeinkeBundeswehr Institute of Radiobiology, Munich, Germany.
Laure BobykDepartment of Radiation Biological Effects, French Armed Forces Biomedical Research Institute, Brétigny-sur-Orge, France.
Eric GregoireInstitut de Radioprotection et de Sureté Nucléaire (IRSN), PSE-SANTE / SERAMED / LRAcc, Fontenay-aux-Roses, F- 92260, France.ORCID 0000-0002-2391-1160
Rositsa HristovaRadiobiology Department, National Centre of Radiobiology and Radiation Protection, Sofia, Bulgaria.
Juan S MartinezInstitut de Radioprotection et de Sureté Nucléaire (IRSN), PSE-SANTE / SERAMED / LRAcc, Fontenay-aux-Roses, F- 92260, France.
Prabodha Kumar MeherCenter for Radiation Protection Research, Department of Molecular Biosciences, The Wenner- Gren Institute, Stockholm University, Stockholm, Sweden.ORCID 0000-0002-2339-6197
Marcela MilanovaDepartment of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czech Republic.ORCID 0000-0002-0366-8124
Octávia Monteiro GilCentro de Ciências e Tecnologias Nucleares, Departamento de Engenharia e Ciências Nucleares, Instituto Superior Técnico (IST), Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0003-1662-1592
Alegria MontoroService of Radiological Protection, Clinical Area of Medical Image, University and Polytechnic La Fe Hospital, Valencia, Spain.ORCID 0000-0003-0448-4607
Jayne MoquetRadiation Effects Department, UK Health Security Agency, Radiation, Chemicals, Climate and Environmental Hazards Directorate, Chilton, UK.
Mercedes Moreno DomeneLaboratorio de Dosimetría Biológica. Servicio de Oncología Radioterápica, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
María Jesús PrietoLaboratorio de Dosimetría Biológica. Servicio de Oncología Radioterápica, Hospital General Universitario Gregorio Marañon, Madrid, Spain.ORCID 0000-0002-7403-9683
Monica Pujol-CanadellUnitat d'Antropologia Biològica, Departament de Biologia Animal, Biologia Vegetal i Ecologia, Universitat Autònoma de Barcelona, Bellaterra, E-08193, Catalonia, Spain.ORCID 0000-0003-2205-0503
Mingzhu SunRadiation Effects Department, UK Health Security Agency, Radiation, Chemicals, Climate and Environmental Hazards Directorate, Chilton, UK.ORCID 0000-0001-6213-5072
Georgia I TerzoudiHealth Physics, Radiobiology and Cytogenetics Laboratory, Institute of Nuclear and Radiological Sciences and Technology, Energy and Safety, National Centre for Scientific Research 'Demokritos', Athens, Greece.ORCID 0000-0002-8262-5703
Ales TichyDepartment of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czech Republic.ORCID 0000-0001-7879-6561
Sotiria TriantopoulouHealth Physics, Radiobiology and Cytogenetics Laboratory, Institute of Nuclear and Radiological Sciences and Technology, Energy and Safety, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Marco ValenteDepartment of Radiation Biological Effects, French Armed Forces Biomedical Research Institute, Brétigny-sur-Orge, France.
Anne VralRadiobiology Lab, Department of Human Structure and Repair, Ghent University, Gent, Belgium.ORCID 0000-0002-3951-774X
Andrzej WojcikRadiobiology Department, National Centre of Radiobiology and Radiation Protection, Sofia, Bulgaria.
Ursula OestreicherDepartment of Effects and Risks of Lonising and Non-Ionising Radiation, Federal Office for Radiation Protection (BfS), Oberschleissheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In previous RENEB interlaboratory comparisons based on the manual scoring of dicentric chromosomes, a tendency for systematic overestimation for doses > 2.5 Gy was found. However, these exercises included only very few doses in the high dose range, and they were heterogeneous in terms of radiation quality and evaluation mode, and comparable only to a limited extent. Here, this presumed deviation was explored by investigating three doses > 2.5 Gy. Blood samples were irradiated (2.56, 3.41 and 4.54 Gy) using a

Indexed as

Chromosome AberrationsCobalt RadioisotopesRadiometryDose-Response Relationship, RadiationHumansLaboratoriesRadiation DosageCobalt-60Cobalt RadioisotopesBiological dosimetryDicentric chromosomeInterlaboratory comparisonIonising radiationNetworkRadiation accident

Identifiers

PMID39952996
PMCPMC11828874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.